Department of Digestive and Metabolic Surgery, Amiens University Medical Center and Jules Verne University of Picardie, North Hospital, Place Victor Pauchet, 80054 Amiens Cedex 01, France.
Obes Surg. 2012 May;22(5):712-20. doi: 10.1007/s11695-012-0597-0.
Laparoscopic sleeve gastrectomy (LSG) has a specific morbidity profile in which gastric leak (GL) is the main complication. With a view to defining a standardized protocol for GL management, the present retrospective study sought to describe the clinical patterns of post-LSG GL and treatment of the latter in our university medical center. From July 2004 to December 2010, 25 patients were included. GL was described in terms of clinical presentation, time to onset, and location in the staple line. Treatment of GL with pharmacologic, radiologic, endoscopic, and/or surgical procedures was always validated by a multidisciplinary care team. "Treatment success" was defined as the absence of contrast agent leakage on CT and endoscopy after removal of covered metallic stent or pigtail drains. Systemic inflammation and peritonitis were the main signs for early-onset GL (56%), whereas pulmonary symptoms and intra-abdominal abscesses revealed delayed-onset GL (44%). Surgery was always performed for early-onset GL. In the total study population, the median number of endoscopic procedures was five (range, 1-11) per patient, of covered SEMS was three (range, 1-8), and of pigtail drains was three (range, 1-4). Nine (36%) patients presented endoscopic-related complications. Four (16%) patients with treatment failure underwent radical surgery. The mortality rate was 4% (n = 1). The management of post-LSG GL is challenging. Surgery was always performed for early-onset GL, whereas treatment of delayed-onset GL was based on endoscopy. Pigtail drains required fewer procedures per patient, were better tolerated, and had lower morbidity-mortality than covered SEMS.
腹腔镜袖状胃切除术(LSG)具有特定的发病率特征,其中胃漏(GL)是主要并发症。为了定义 GL 管理的标准化方案,本回顾性研究旨在描述我们大学医学中心 LSG 后 GL 的临床模式和后者的治疗方法。从 2004 年 7 月至 2010 年 12 月,共纳入 25 例患者。GL 根据临床表现、发病时间和吻合线位置进行描述。GL 的治疗采用药物、放射、内镜和/或手术方法,始终由多学科护理团队验证。“治疗成功”定义为在移除覆盖金属支架或猪尾引流管后 CT 和内镜检查无造影剂渗漏。全身炎症和腹膜炎是早期 GL(56%)的主要表现,而肺部症状和腹腔脓肿则表明晚期 GL(44%)。早期 GL 总是需要手术治疗。在总研究人群中,中位内镜治疗次数为 5 次(范围 1-11 次)/患者,中位覆盖 SEMS 次数为 3 次(范围 1-8 次),中位猪尾引流管次数为 3 次(范围 1-4 次)。9 例(36%)患者出现内镜相关并发症。4 例(16%)治疗失败的患者接受了根治性手术。死亡率为 4%(n=1)。LSG 后 GL 的管理具有挑战性。早期 GL 总是需要手术治疗,而晚期 GL 的治疗则基于内镜。与覆盖 SEMS 相比,猪尾引流管每例患者所需的操作次数更少,耐受性更好,且发病率和死亡率更低。