Martínez Hernández Andreu, Beltrán Herrera Homero, Martínez García Vicente, Ibáñez Belenguer Miguel, Queralt Martín Raquel, Maiocchi Segredo Ana Karina, Aliaga Hilario Elena, Laguna Sastre José Manuel
Department of General Surgery, University General Hospital, Castellon, Spain.
Department of Mathematics, Jaume I University, Castellon, Spain.
Obes Surg. 2022 Apr;32(4):1034-1048. doi: 10.1007/s11695-022-05890-8. Epub 2022 Feb 7.
Despite the low rates of complications of bariatric surgery, gastrointestinal leaks are major adverse events that increase post-operative morbidity and mortality. Endoscopic treatment using self-expanding stents has been used in the therapeutic management of these complications with preliminary good results.
We performed a systematic review and meta-analysis of self-expanding stents placement for the management of gastrointestinal leaks after obesity surgery. Overall proportion of successful leak closure, stent migration, and reoperation were analysed as primary outcomes. Secondary outcomes were patients' clinical characteristics, duration and type of stent, other stent complications, and mortality.
A meta-analysis of studies reporting stents was performed, including 488 patients. The overall proportion of successful leak closure was 85.89% (95% CI, 82.52-89.25%), median interval between stent placement and its removal of 44 days. Stent migration was noted in 18.65% (95% CI, 14.32-22.98%) and the overall proportion of re-operation was in 13.54% (95% CI, 9.94-17.14%). The agreement between reviewers for the collected data gave a Cohen's κ value of 1.0. No deaths were caused directly by complications with the stent placement.
Endoscopic placement of self-expanding stents can be used, in selected patients, for the management of leaks after bariatric surgery with a high rate of effectiveness and low mortality rates. Nevertheless, reducing stent migration and re-operation rates represents an important challenge for future studies.
尽管减肥手术的并发症发生率较低,但胃肠道漏是主要的不良事件,会增加术后发病率和死亡率。使用自膨式支架的内镜治疗已用于这些并发症的治疗管理,初步取得了良好效果。
我们对肥胖手术后使用自膨式支架治疗胃肠道漏进行了系统评价和荟萃分析。分析成功封闭漏口的总体比例、支架移位和再次手术作为主要结局。次要结局包括患者的临床特征、支架的持续时间和类型、其他支架并发症以及死亡率。
对报告支架治疗的研究进行了荟萃分析,包括488例患者。成功封闭漏口的总体比例为85.89%(95%置信区间,82.52 - 89.25%),支架置入与取出之间的中位间隔为44天。支架移位发生率为18.65%(95%置信区间,14.32 - 22.98%),再次手术的总体比例为13.54%(95%置信区间,9.94 - 17.14%)。 reviewers对收集数据的一致性Cohen's κ值为1.0。支架置入并发症未直接导致死亡。
对于部分患者,内镜下置入自膨式支架可用于治疗减肥手术后的漏口,有效率高且死亡率低。然而,降低支架移位和再次手术率是未来研究的一项重要挑战。