Understanding and overcoming chemoresistance in ovarian cancer: emerging role of the endothelin axis.
作者信息
Bagnato A, Rosanò L
机构信息
Molecular Pathology Laboratory A, Regina Elena National Cancer Institute, Rome, Italy.
出版信息
Curr Oncol. 2012 Feb;19(1):36-8. doi: 10.3747/co.19.895.
Abstract
摘要
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本文引用的文献
1
Hallmarks of cancer: the next generation.癌症的特征：下一代。
Cell. 2011 Mar 4;144(5):646-74. doi: 10.1016/j.cell.2011.02.013.
2
Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells.化学耐药性和 EMT 表型的获得与卵巢癌细胞内皮素 A 受体途径的激活有关。
Clin Cancer Res. 2011 Apr 15;17(8):2350-60. doi: 10.1158/1078-0432.CCR-10-2325. Epub 2011 Jan 10.
3
The importance of endothelin axis in initiation, progression, and therapy of ovarian cancer.内皮素轴在卵巢癌的发生、发展和治疗中的重要性。
Am J Physiol Regul Integr Comp Physiol. 2010 Aug;299(2):R395-404. doi: 10.1152/ajpregu.00304.2010. Epub 2010 Jun 10.
4
Epithelial mesenchymal transition and cancer stem cell-like phenotypes facilitate chemoresistance in recurrent ovarian cancer.上皮间质转化和癌症干细胞样表型促进复发性卵巢癌的化疗耐药性。
Curr Cancer Drug Targets. 2010 May;10(3):268-78. doi: 10.2174/156800910791190175.
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Pathway analysis of gene lists associated with platinum-based chemotherapy resistance in ovarian cancer: the big picture.与卵巢癌铂类化疗耐药相关基因列表的通路分析：全局观。
Gynecol Oncol. 2010 May;117(2):170-6. doi: 10.1016/j.ygyno.2010.01.010. Epub 2010 Feb 4.
6
Snail is critical for tumor growth and metastasis of ovarian carcinoma.蜗牛对卵巢癌的肿瘤生长和转移至关重要。
Int J Cancer. 2010 May 1;126(9):2102-11. doi: 10.1002/ijc.24901.
7
The biology of ovarian cancer: new opportunities for translation.卵巢癌生物学：转化医学的新机遇
Nat Rev Cancer. 2009 Jun;9(6):415-28. doi: 10.1038/nrc2644.
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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits.上皮细胞与间充质细胞状态之间的转变：恶性特征和干细胞特征的获得。
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The epithelial-mesenchymal transition generates cells with properties of stem cells.上皮-间质转化产生具有干细胞特性的细胞。
Cell. 2008 May 16;133(4):704-15. doi: 10.1016/j.cell.2008.03.027.
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