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本文引用的文献

1
Pathophysiology and treatment of myoclonus.肌阵挛的病理生理学与治疗
Neurol Clin. 2009 Aug;27(3):757-77, vii. doi: 10.1016/j.ncl.2009.04.002.
2
Tonic spasms in acute transverse myelitis.
J Clin Neurosci. 2009 Jan;16(1):165-6. doi: 10.1016/j.jocn.2008.05.007. Epub 2008 Nov 18.
3
Pathophysiology of spinal myoclonus.
Adv Neurol. 2002;89:137-44.
4
Intrathecal baclofen therapy for stiff-man syndrome and progressive encephalomyelopathy with rigidity and myoclonus.鞘内注射巴氯芬治疗僵人综合征及伴有僵硬和肌阵挛的进行性脑脊髓病。
Neurology. 1997 Dec;49(6):1591-7. doi: 10.1212/wnl.49.6.1591.

鞘内注射巴氯芬治疗脊髓性肌阵挛：病例系列

Intrathecal baclofen for the treatment of spinal myoclonus: a case series.

作者信息

Chiodo Anthony E, Saval April

机构信息

University of Michigan Medical Center, Ann Arbor, MI, USA.

出版信息

J Spinal Cord Med. 2012 Jan;35(1):64-7. doi: 10.1179/2045772311Y.0000000006.

DOI:10.1179/2045772311Y.0000000006
PMID:22330193
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3240919/
Abstract

CONTEXT/OBJECTIVE: To demonstrate the utility of intrathecal baclofen in the treatment of secondary myoclonus of spinal origin.

DESIGN

Case series.

SETTING

University medical center.

PARTICIPANTS

Two patients with spinal myoclonus who required the use of an assistive device because of difficulty walking resulting in falls.

INTERVENTIONS

Intrathecal baclofen management.

OUTCOME MEASURES

Symptom management and mobility function.

RESULTS

Both experienced resolution of their spinal myoclonus and became community-level ambulators without the need of an assistive device.

CONCLUSION

Intrathecal baclofen is an effective treatment of secondary myoclonus of spinal origin.

摘要

背景/目的：证明鞘内注射巴氯芬在治疗脊髓源性继发性肌阵挛中的效用。

设计

病例系列。

地点

大学医学中心。

参与者

两名脊髓性肌阵挛患者，因行走困难导致跌倒而需要使用辅助装置。

干预措施

鞘内注射巴氯芬治疗。

观察指标

症状管理和运动功能。

结果

两名患者的脊髓性肌阵挛均得到缓解，无需辅助装置即可在社区水平行走。

结论

鞘内注射巴氯芬是治疗脊髓源性继发性肌阵挛的有效方法。