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控制能量平衡的电路的电生理分析。

Electrophysiological analysis of circuits controlling energy homeostasis.

机构信息

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

出版信息

Mol Neurobiol. 2012 Apr;45(2):258-78. doi: 10.1007/s12035-012-8241-5. Epub 2012 Feb 14.

Abstract

Since the discovery of leptin and the central melanocortin circuit, electrophysiological studies have played a major role in elucidating mechanisms underlying energy homeostasis. This review highlights the contribution of findings made by electrophysiological measurements to the current understanding of hypothalamic neuronal networks involved in energy homeostasis with a specific focus on the arcuate-paraventricular nucleus circuit.

摘要

自瘦素和中枢黑皮质素回路被发现以来,电生理学研究在阐明能量平衡的机制方面发挥了重要作用。本综述重点介绍了电生理测量发现对当前理解参与能量平衡的下丘脑神经元网络的贡献,特别是弓状核-室旁核回路。

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