Krug Kathrin Barbara, Stützer Hartmut, Frommolt Peter, Boecker Julia, Bovenschulte Henning, Sendler Volker, Lackner Klaus
Department of Radiology, Medical School, University of Cologne, Kerpenerstraße 62, 50924 Cologne, Germany.
Int J Breast Cancer. 2011;2011:701054. doi: 10.4061/2011/701054. Epub 2010 Oct 17.
To compare the detection of microcalcifications on mammograms of an anthropomorphic breast phantom acquired by a direct digital flat-panel detector mammography system (FPM) versus a stereotactic breast biopsy system utilizing CCD (charge-coupled device) technology with either a 1024 or 512 acquisition matrix (1024 CCD and 512 CCD).
Randomly distributed silica beads (diameter 100-1400 μm) and anthropomorphic scatter bodies were applied to 48 transparent films. The test specimens were radiographed on a direct digital FPM and by the indirect 1024 CCD and 512 CCD techniques. Four radiologists rated the monitor-displayed images independently of each other in random order.
The rate of correct positive readings for the "number of detectable microcalcifications" for silica beads of 100-199 μm in diameter was 54.2%, 50.0% and 45.8% by FPM, 1024 CCD and 512 CCD, respectively. The inter-rater variability was most pronounced for silica beads of 100-199 μm in diameter. The greatest agreement with the gold standard was observed for beads >400 μm in diameter across all methods.
Stereotactic spot images taken by 1024 matrix CCD technique are diagnostically equivalent to direct digital flat-panel mammograms for visualizing simulated microcalcifications >400 μm in diameter.
比较直接数字化平板探测器乳腺摄影系统(FPM)与采用电荷耦合器件(CCD)技术且具有1024或512采集矩阵(1024 CCD和512 CCD)的立体定向乳腺活检系统对拟人化乳腺模型乳房X线照片上微钙化的检测情况。
将随机分布的硅珠(直径100 - 1400μm)和拟人化散射体应用于48张透明胶片。测试标本在直接数字化FPM以及间接1024 CCD和512 CCD技术下进行射线照相。四位放射科医生以随机顺序独立对显示器上显示的图像进行评级。
对于直径为100 - 199μm的硅珠,FPM、1024 CCD和512 CCD检测到的“可检测微钙化数量”的正确阳性读数率分别为54.2%、50.0%和45.8%。对于直径为100 - 199μm的硅珠,评分者间的变异性最为明显。在所有方法中,对于直径>400μm的珠子,与金标准的一致性最高。
采用1024矩阵CCD技术拍摄的立体定向点片在诊断上等同于直接数字化平板乳房X线照片,用于显示直径>400μm的模拟微钙化。