Kobayashi Kiyoyuki, Himoto Takashi, Tani Joji, Miyoshi Hisaaki, Yoneyama Hirohito, Deguchi Akihiro, Kurokohchi Kazutaka, Mori Hirohito, Hoshikawa Hiroshi, Ueno Masaki, Masaki Tsutomu
Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Japan.
Intern Med. 2012;51(4):381-5. doi: 10.2169/internalmedicine.51.6764. Epub 2012 Feb 15.
Metastasis to lymph nodes in patients with hepatocellular carcinoma (HCC) is generally observed to occur in regional chains of involvement. We encountered a HCC patient who had hepatitis C virus-related liver cirrhosis and portal vein tumor thrombosis, accompanied by metastasis to only a single cervical lymph node, skipping the common intermediate routes of involvement. It is noteworthy, so as not to miss the clinical diagnosis, to remark that metastasis to the cervical lymph node is rarely observed in patients with HCC, and that the metastasis can skip to the regional lymph nodes.
肝细胞癌（HCC）患者发生淋巴结转移通常见于区域受累链。我们遇到一名患有丙型肝炎病毒相关性肝硬化和门静脉肿瘤血栓形成的HCC患者，仅伴有单个颈部淋巴结转移，跳过了常见的中间受累途径。值得注意的是，为了不遗漏临床诊断，HCC患者很少观察到颈部淋巴结转移，且转移可跳跃至区域淋巴结。
