Department of Electrical Engineering and Computer Science, University of California, Irvine, CA 92697, USA.
IEEE Trans Biomed Eng. 2012 May;59(5):1339-48. doi: 10.1109/TBME.2012.2187336. Epub 2012 Feb 10.
Source signals that have strong temporal correlation can pose a challenge for high-resolution EEG source localization algorithms. In this paper, we present two methods that are able to accurately locate highly correlated sources in situations where other high-resolution methods such as multiple signal classification and linearly constrained minimum variance beamforming fail. These methods are based on approximations to the optimal maximum likelihood (ML) approach, but offer significant computational advantages over ML when estimates of the equivalent EEG dipole orientation and moment are required in addition to the source location. The first method uses a two-stage approach in which localization is performed assuming an unstructured dipole moment model, and then the dipole orientation is obtained by using these estimates in a second step. The second method is based on the use of the noise subspace fitting concept, and has been shown to provide performance that is asymptotically equivalent to the direct ML method. Both techniques lead to a considerably simpler optimization than ML since the estimation of the source locations and dipole moments is decoupled. Examples using data from simulations and auditory experiments are presented to illustrate the performance of the algorithms.
源信号具有很强的时间相关性,这给高分辨率 EEG 源定位算法带来了挑战。在本文中,我们提出了两种方法,即使在多信号分类和线性约束最小方差波束形成等其他高分辨率方法失败的情况下,也能够准确地定位高度相关的源。这些方法基于对最优最大似然(ML)方法的近似,但与 ML 相比,当除了源位置之外还需要估计等效 EEG 偶极子方向和矩时,它们具有显著的计算优势。第一种方法使用两阶段方法,其中在假设无结构偶极子矩模型的情况下进行定位,然后通过在第二步中使用这些估计值来获得偶极子方向。第二种方法基于使用噪声子空间拟合概念,已被证明提供与直接 ML 方法渐近等效的性能。由于源位置和偶极子矩的估计解耦,这两种技术都导致了比 ML 更简单的优化。使用来自模拟和听觉实验的数据的示例说明了算法的性能。