Karathanasis Konstantinos T, Gouzouasis Ioannis A, Karanasiou Irene S, Uzunoglu Nikolaos K
Department of Electrical and Computer Engineering, National Technical University of Athens, Athens 15780, Greece.
IEEE Trans Inf Technol Biomed. 2012 Mar;16(2):241-7. doi: 10.1109/TITB.2012.2187301. Epub 2012 Feb 10.
This paper presents the latest progress made concerning a hybrid diagnostic and therapeutic system able to provide focused microwave radiometric temperature and/or conductivity variation measurements and hyperthermia treatment. Previous experimental studies of our group have demonstrated the system performance and focusing properties in phantom as well as human experiments. The system is able to detect temperature and conductivity variations with frequency-dependent detection depth and spatial sensitivity. Numerous studies have also demonstrated the improvement of the system focusing properties attributed to the use of dielectric and left handed matching layers. In this study, similar experimental procedures are performed but this time using an anatomical head model as phantom aiming to achieve a more accurate modeling of the system's future real function. This way, another step is made toward the deeper understanding of the system's capabilities, with the view to further use it in experimental procedures with laboratory animals and human volunteers.
本文介绍了一种能够提供聚焦微波辐射温度和/或电导率变化测量以及热疗的混合诊断与治疗系统的最新进展。我们团队之前的实验研究已经在体模以及人体实验中证明了该系统的性能和聚焦特性。该系统能够检测温度和电导率的变化，其检测深度和空间灵敏度与频率相关。大量研究还表明，由于使用了介电匹配层和左手匹配层，系统的聚焦特性得到了改善。在本研究中，进行了类似的实验程序，但这次使用解剖头部模型作为体模，旨在更准确地模拟系统未来的实际功能。通过这种方式，朝着更深入理解系统的能力又迈进了一步，以期在实验室动物和人类志愿者的实验程序中进一步使用该系统。
