Khorol'skaia M A, Vakhrushev S G, Terskova N V
Vestn Otorinolaringol. 2011(5):59-61.
The objective of the present work was to assess the efficacy of the treatment of chronic rhinosinusitis (CR) in the patients treated with sinuforte using the contact microendoscpic technique. This randomized open clinical and instrumental study included 30 patients presenting with chronic rhinosinusitis. All of them were treated with sinuforte as monotherapy at a dose of 1.3 mg per procedure given once daily during 7 consecutive days. The efficacy of the treatment was evaluated by means of endoscopic and microendoscopic examination supplemented by functional tests on days 1, 2, 4, 6, and 8 after the beginning of therapy. In addition, a questionnaire study was carried out. It was demonstrated that the use of sinuforte for the treatment of the patients with chronic rhinjsinusitis is safe and efficacious as confirmed by the morphological picture revealed by contact microendoscopy.
本研究的目的是评估使用鼻窦福（Sinuforte）并采用接触式显微内镜技术治疗慢性鼻-鼻窦炎（CR）患者的疗效。这项随机开放的临床和仪器研究纳入了30例慢性鼻-鼻窦炎患者。所有患者均接受鼻窦福单一疗法治疗，每次剂量为1.3毫克，连续7天每天给药一次。在治疗开始后的第1、2、4、6和8天，通过内镜和显微内镜检查并辅以功能测试来评估治疗效果。此外，还进行了问卷调查研究。接触式显微内镜所揭示的形态学图像证实，使用鼻窦福治疗慢性鼻-鼻窦炎患者是安全有效的。
