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[猫后睾吸虫与伤寒沙门氏菌的交叉反应抗原及其对伤寒临床病程的可能影响]

[Cross-reacting antigens of Opisthorchis felineus and Salmonella typhi and their possible effect on the clinical course of typhoid fever].

作者信息

Lepekhin A V, Ratner G M, Meniavtseva T A

出版信息

Med Parazitol (Mosk). 1990 Jul-Aug(4):33-6.

PMID:2233535
Abstract

The experiments on rabbits immunized with a complex O. felineus antigen and spirit abdominal typhoid vaccine enriched with Vi-antigen, as well as studies on patients with chronic opisthorchiasis and bacterial carriers of S. typhi have established the presence of cross-reacting antigens in abdominal typhoid and opisthorchiasis pathogens. It is suggested that these antigens play an essential role in the development and outcome of abdominal typhoid secondary to chronic opisthorchiasis invasion.

摘要

用猫后睾吸虫复合抗原和富含Vi抗原的伤寒菌苗免疫家兔的实验,以及对慢性后睾吸虫病患者和伤寒杆菌携带者的研究,均证实了伤寒和后睾吸虫病病原体中存在交叉反应抗原。有人认为,这些抗原在慢性后睾吸虫病侵袭继发伤寒的发生和转归中起重要作用。

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