Price W E
Department of Surgery, University of Minnesota Medical School, Minneapolis.
Minn Med. 1990 Sep;73(9):33-4.
Although most urologists will agree that dealing with patients suffering from the multiple symptom complex commonly called the urethral syndrome is often time consuming, its origin and treatment continue to generate debate. This essay proposes that entrapment of sensory nerves in the wall of the urethra by fibrosis leads to an abnormal response of Barrington's reflex II, which, in turn, leads to the urethral syndrome. Periurethral fibrosis occurs following trauma, infections, and pelvic irradiation therapy. The urethral syndrome, the author concludes, is therefore based on recognized anatomical factors. The recommended treatment is urethral dilation accompanied by hot sits baths and short courses of Sulfamethoxazole-Trimethoprim. Long-term drug therapy is to be avoided.
尽管大多数泌尿科医生都认为，治疗患有通常被称为尿道综合征的多种症状复合体的患者往往很耗时，但其病因和治疗方法仍存在争议。本文提出，尿道壁内感觉神经被纤维化包裹会导致巴林顿反射II异常反应，进而导致尿道综合征。尿道周围纤维化发生在创伤、感染和盆腔放射治疗之后。作者得出结论，尿道综合征因此基于公认的解剖学因素。推荐的治疗方法是尿道扩张，同时进行热水坐浴和短期服用复方新诺明。应避免长期药物治疗。
