[Juvenile xanthogranuloma: 3 cases report and literature review].

OBJECTIVE

To report the clinical characteristics and treatment of 3 patients with juvenile xanthogranuloma (JXG).

METHODS

A retrospective review of the medical records of 3 patients with JXG.

RESULTS

JXG was characterized by solitary or multiple yellowish cutaneous nodules, or eye involvement . It could also affect pituitary. JXG was easily misdiagnosed as Langerhans cell histiocytosis (LCH). Treatment for JXG was surgical excision of a solitary skin lesion and some cases might be, spontaneous regression. In cases with multisystem involvement, chemotherapy regimens used to treat LCH may be effective.

CONCLUSIONS

JXG is one of the more common non-Langerhans histiocytic proliferations and is frequently seen in infants and children. LCH-like chemotherapy is effective for patients with symptomatic multisystem JXG.