Liu Zi-qin, Liu Rong, Shi Xiao-dong, Li Jing-xian, Zou Ji-zhen
The Department of Hematology and Oncology of Capital Institute of Pediatrics, Beijing 100020, China.
Zhonghua Xue Ye Xue Za Zhi. 2011 Sep;32(9):614-7.
To report the clinical characteristics and treatment of 3 patients with juvenile xanthogranuloma (JXG).
A retrospective review of the medical records of 3 patients with JXG.
JXG was characterized by solitary or multiple yellowish cutaneous nodules, or eye involvement . It could also affect pituitary. JXG was easily misdiagnosed as Langerhans cell histiocytosis (LCH). Treatment for JXG was surgical excision of a solitary skin lesion and some cases might be, spontaneous regression. In cases with multisystem involvement, chemotherapy regimens used to treat LCH may be effective.
JXG is one of the more common non-Langerhans histiocytic proliferations and is frequently seen in infants and children. LCH-like chemotherapy is effective for patients with symptomatic multisystem JXG.
报告3例幼年性黄色肉芽肿（JXG）患者的临床特征及治疗情况。
对3例JXG患者的病历进行回顾性分析。
JXG的特征为孤立或多发的淡黄色皮肤结节，或累及眼部，也可影响垂体。JXG易被误诊为朗格汉斯细胞组织细胞增多症（LCH）。JXG的治疗方法为手术切除孤立的皮肤病变，部分病例可能会自发消退。对于多系统受累的病例，用于治疗LCH的化疗方案可能有效。
JXG是较常见的非朗格汉斯组织细胞增生症之一，常见于婴幼儿。对于有症状的多系统JXG患者，类似LCH的化疗有效。
