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定量临床电生理学在神经损伤与再生评估中的应用

Quantitative clinical electrophysiology in the evaluation of nerve injury and regeneration.

作者信息

Dorfman L J

机构信息

Department of Neurology and Neurological Sciences, Stanford University School of Medicine, CA 94305.

出版信息

Muscle Nerve. 1990 Sep;13(9):822-8. doi: 10.1002/mus.880130908.

DOI:10.1002/mus.880130908
PMID:2233868
Abstract

Neuromuscular electrophysiological techniques can provide clinically important information about the localization, severity, and pathophysiology of peripheral nerve injuries, and about the progress of reinnervation. The relevant variables for study are compound nerve and muscle action potentials, motor unit action potentials, and denervation potentials. Available methods do not permit meaningful quantitation of regeneration. Newer methods under development attempt to estimate the number of motor units in a muscle and the number of axons in a nerve.

摘要

神经肌肉电生理技术能够提供有关周围神经损伤的定位、严重程度及病理生理学,以及再支配进展的重要临床信息。研究的相关变量包括复合神经动作电位、肌肉动作电位、运动单位动作电位及失神经电位。现有的方法无法对再生进行有意义的定量分析。正在研发的新方法试图估算肌肉中运动单位的数量以及神经中轴突的数量。

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