泰国东北部孔敬府城区老年男性维生素D缺乏症的患病率。

Prevalence of vitamin D insufficiency among the elderly males living in the urban areas of Khon Kaen Province in the northeast of Thailand.

作者信息

Soontrapa Suppasin, Soontrapa Sukree, Chaikitpinyo Sakda

机构信息

Department of Orthopaedics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

出版信息

J Med Assoc Thai. 2011 Oct;94 Suppl 5:S59-62.

PMID:22338929

Abstract

BACKGROUND

Vitamin D insufficiency among the elderly Thai women in the urban areas was higher than in the rural areas because of lifestyle differences. There are very few studies about vitamin D status among Thai elderly males.

OBJECTIVE

To ascertain the vitamin D status in and prevalence of vitamin D insufficiency among the elderly Thai males living in the urban areas of Khon Kaen province, situated in Northeast, Thailand.

RESULTS

The respective mean (SE) of calcidiol, beta-CTx and PINP level for the elderly Thai males were 42.04 (1.22), 0.26 (0.02) and 37.39 (2.19) ng/mL. A calcidiol level under 40 ng/mL indicated vitamin D insufficiency and the prevalence of the elderly Thai males living in urban area of Khon Kaen province, Thailand was 48%. The respective correlations between PTH and calcidiol, beta-CTx and PINP were -0.217, 0.640 and 0.393. The respective correlations between PTH and BMD of the trochanteric region and total femur were 0.198 and 0.199 (p < 0.05).

CONCLUSION

The prevalence of vitamin D insufficiency among the elderly males in Khon Kaen remained high and the bone biochemical markers were at a low enough level to cause low bone turnover and low BMD.

摘要

背景

由于生活方式的差异，泰国城市老年女性维生素D缺乏的情况比农村地区更为严重。关于泰国老年男性维生素D状况的研究非常少。

目的

确定泰国东北部孔敬府城市地区老年男性的维生素D状况以及维生素D缺乏的患病率。

结果

泰国老年男性骨化二醇、β-羧基端胶原交联（β-CTx）和I型前胶原氨基端前肽（PINP）水平的各自均值（标准误）分别为42.04（1.22）、0.26（0.02）和37.39（2.19）ng/mL。骨化二醇水平低于40 ng/mL表明维生素D缺乏，泰国孔敬府城市地区老年男性的患病率为48%。甲状旁腺激素（PTH）与骨化二醇、β-CTx和PINP之间的相关系数分别为-0.217、0.640和0.393。PTH与转子区和全股骨骨密度（BMD）之间的相关系数分别为0.198和0.199（p<0.05）。