Yan Zhimin, Ding Ning, Liu Xiaosong, Hua Hong
Department of Oral Medicine, Peking University School and Hospital of Stomatology, Beijing, China.
Acta Otolaryngol. 2012 Jun;132(6):671-5. doi: 10.3109/00016489.2011.648273. Epub 2012 Feb 16.
Abstract Congenital agenesis of the salivary glands is an extremely rare congenital condition, which may cause severe xerostomia, progressive dental caries, and oropharyngeal candidiasis in children. To date, there have been few documented cases of aplasia of the major salivary glands. Congenital agenesis of the salivary glands accompanied by absence of the lacrimal puncta is even more rare. We report a case of a 5-year-old boy with xerostomia and extensive dental caries. Salivary gland imaging with sodium pertechnetate 99mTcO(4) showed bilateral aplasia of the parotid, submandibular, and sublingual glands. The patient was found to lack the left lacrimal puncta through physical examination. Here we describe the clinical presentation, diagnostic essentials, and medical and dental management of the patient.
摘要 唾液腺先天性发育不全是一种极为罕见的先天性疾病，可导致儿童严重口干、进行性龋齿和口咽念珠菌病。迄今为止，主要唾液腺发育不全的病例记录很少。伴有泪点缺失的唾液腺先天性发育不全更为罕见。我们报告一例5岁男孩，有口干和广泛龋齿。用99mTcO(4)高锝酸钠进行唾液腺显像显示双侧腮腺、颌下腺和舌下腺发育不全。通过体格检查发现该患者左侧泪点缺失。在此我们描述该患者的临床表现、诊断要点以及医疗和牙科处理情况。
