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英格兰重复横断面调查中抑郁的年龄和出生队列差异:1993 年至 2007 年的全国精神疾病发病率调查。

Age and birth cohort differences in depression in repeated cross-sectional surveys in England: the National Psychiatric Morbidity Surveys, 1993 to 2007.

机构信息

Department of Health Sciences, University of Leicester, UK.

出版信息

Psychol Med. 2012 Oct;42(10):2047-55. doi: 10.1017/S003329171200013X. Epub 2012 Feb 17.

Abstract

BACKGROUND

The National Psychiatric Morbidity Survey (NPMS) programme was partly designed to monitor trends in mental disorders, including depression, with comparable data spanning 1993 to 2007. Findings already published from this programme suggest that concerns about increasing prevalence of common mental disorders (CMDs) may be unfounded. This article focuses on depression and tests the hypothesis that successive birth cohorts experience the same prevalence of depression as they age.

METHOD

We carried out a pseudo-cohort analysis of a sequence of three cross-sectional surveys of the English household population using identical diagnostic instruments. The main outcome was ICD-10 depressive episode or disorder. Secondary outcomes were the depression subscales of the Clinical Interview Schedule - Revised (CIS-R).

RESULTS

There were 8670, 6977 and 6815 participants in 1993, 2000 and 2007 respectively. In men, the prevalence of depression increased between cohorts born in 1943-1949 and 1950-1956 [odds ratio (OR) 2.5, 95% confidence interval (CI) 1.4-4.2], then remained relatively stable across subsequent cohorts. In women, there was limited evidence of change in prevalence of depression. Women born in 1957-1963, surveyed aged 44-50 years in 2007, had exceptionally high prevalence. It is not clear whether this represents a trend or a quirk of sampling.

CONCLUSIONS

There is no evidence of an increase in the prevalence of depression in male cohorts born since 1950. In women, there is limited evidence of increased prevalence. Demand for mental health services may stabilize or even fall for men.

摘要

背景

国家精神疾病发病率调查(NPMS)项目的部分设计目的是监测精神障碍(包括抑郁症)的趋势,其数据可追溯至 1993 年至 2007 年。该项目已发表的研究结果表明,对常见精神障碍(CMD)患病率增加的担忧可能没有依据。本文重点关注抑郁症,并检验了这样一个假设,即连续的出生队列随着年龄的增长,其抑郁症的患病率相同。

方法

我们使用相同的诊断工具,对连续三次针对英国家庭人口的横断面调查进行了伪队列分析。主要结局是 ICD-10 抑郁发作或障碍。次要结局是临床访谈表修订版(CIS-R)的抑郁子量表。

结果

1993 年、2000 年和 2007 年分别有 8670、6977 和 6815 名参与者。在男性中,出生于 1943-1949 年和 1950-1956 年的队列中,抑郁症的患病率在队列间增加[比值比(OR)2.5,95%置信区间(CI)1.4-4.2],随后在随后的队列中相对稳定。在女性中,抑郁症患病率变化的证据有限。在 2007 年接受 44-50 岁调查的出生于 1957-1963 年的女性中,患病率异常高。目前尚不清楚这是代表一种趋势还是抽样的怪癖。

结论

自 1950 年以来出生的男性队列中,抑郁症的患病率没有增加的证据。在女性中,有有限的证据表明患病率增加。男性对心理健康服务的需求可能会稳定甚至下降。

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