Department of Orthopaedics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Chin Med J (Engl). 2011 Dec;124(23):3886-90.
Assessing the radiographic features of knee osteoarthritis (OA), especially joint space narrowing, is important for evaluating disease progression. The purpose of this study was to quantitatively analyze joint space narrowing by measuring 2 new variables: the average joint space width (aJSW) and the articulate angle (AA) on X-ray films, and to evaluate the relationship between the 2 variables, knee function and OA symptoms.
Using the web-based radiology viewer (Cedara I-Reach™ 4.1.1), we measured the 2 variables in 50 knees of 41 patients with knee OA participating in the Shanghai OA Study. We also evaluated the Kellgren-Lawrence (K-L) grade, the Western Ontario and McMaster Universities OA Index (WOMAC), and additional questionnaire in OA knees. The study was approved by the ethics committee of Shanghai Ninth People's Hospital (No. 2009 - 28).
The aJSW correlated with the K-L grade (r = -0.57, P < 0.001), kneeling (r = -0.29, P = 0.04), sitting cross-legged on the floor (r = -0.31, P = 0.03), WOMAC pain (r = -0.31, P = 0.03), WOMAC disability (r = -0.35, P = 0.01), pain while squatting (r = -0.37, P = 0.01), and defecating in a squatting position (r = -0.39, P = 0.01). The AA correlated with defecating in a squatting position (r = 0.29, P = 0.05), WOMAC disability (r = 0.30, P = 0.04) and K-L grade (r = 0.44, P = 0.003). The K-L grade also correlated with pain while squatting (r = -0.40, P = 0.005) and defecating in a squatting position (r = -0.34, P = 0.02), WOMAC pain (r = 0.30, P = 0.04), and WOMAC disability (r = 0.30, P = 0.04).
The aJSW closely correlated with knee OA symptoms and function scores, and was more sensitive to knee OA related disabilities than K-L grade and the AA. The aJSW could be used as a new variable for knee OA evaluation.
评估膝关节骨关节炎（OA）的放射学特征，尤其是关节间隙变窄，对于评估疾病进展非常重要。本研究的目的是通过测量 X 射线片上的两个新变量：平均关节间隙宽度（aJSW）和关节角（AA），对关节间隙变窄进行定量分析，并评估这两个变量与膝关节功能和 OA 症状之间的关系。
使用基于网络的放射学查看器（Cedara I-Reach™4.1.1），我们在 41 名膝关节 OA 患者的 50 个膝关节中测量了这两个变量。我们还评估了 Kellgren-Lawrence（K-L）分级、西安大略和麦克马斯特大学骨关节炎指数（WOMAC）以及 OA 膝关节的其他问卷。该研究得到了上海第九人民医院伦理委员会的批准（编号：2009-28）。
aJSW 与 K-L 分级（r=-0.57，P<0.001）、下跪（r=-0.29，P=0.04）、盘腿坐在地板上（r=-0.31，P=0.03）、WOMAC 疼痛（r=-0.31，P=0.03）、WOMAC 残疾（r=-0.35，P=0.01）、深蹲时疼痛（r=-0.37，P=0.01）和蹲位排便（r=-0.39，P=0.01）相关。AA 与蹲位排便（r=0.29，P=0.05）、WOMAC 残疾（r=0.30，P=0.04）和 K-L 分级（r=0.44，P=0.003）相关。K-L 分级还与深蹲时疼痛（r=-0.40，P=0.005）和蹲位排便（r=-0.34，P=0.02）、WOMAC 疼痛（r=0.30，P=0.04）和 WOMAC 残疾（r=0.30，P=0.04）相关。
aJSW 与膝关节 OA 症状和功能评分密切相关，与 K-L 分级和 AA 相比，aJSW 对膝关节 OA 相关残疾更敏感。aJSW 可作为膝关节 OA 评估的新变量。
