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[Severe atropine poisoning mimicking acute stroke].

作者信息

Faivre A, Mounier C, Gaillard T, Alla P, Goutorbe P

机构信息

Unité neurovasculaire, service de neurologie, hôpital d'instruction des armées Sainte-Anne, boulevard Saint-Anne, Toulon cedex 09, France.

出版信息

Rev Neurol (Paris). 2012 May;168(5):450-3. doi: 10.1016/j.neurol.2011.09.009. Epub 2012 Feb 14.

DOI:10.1016/j.neurol.2011.09.009
PMID:22340863
Abstract

INTRODUCTION

Atropine is a strong antagonist of muscarinic receptors widely used in various diseases because of its anticholinergic action.

CASE-REPORT: We report here a case of accidental poisoning due to ingestion of atropine eyes drops that caused severe neurologic disorders mimicking an acute stroke. Correct diagnosis was finally made by detecting atropine in the cerebrospinal fluid of the patient.

CONCLUSIONS

Atropinic poisoning can induce misleading neuropsychiatric disorders mimicking stroke. Therefore, this diagnosis should be considered in patients presenting an unexplained encephalopathy with anticholinergic manifestations, especially when bilateral mydriasis occurs.

摘要

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