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[库欣综合征与妊娠:关于一例恶性肾上腺皮质癌]

[Cushing syndrome and pregnancy: a propos of a malignant adrenocortical carcinoma].

作者信息

Homer L, Viatge M, Gayet F-X, Laurent Y, Kerlan V

机构信息

Service de gynécologie obstétrique et médecine de la reproduction, CHU de Brest, Brest, France.

出版信息

Gynecol Obstet Fertil. 2012 Mar;40(3):e1-4. doi: 10.1016/j.gyobfe.2011.07.053. Epub 2012 Feb 16.

Abstract

Cushing's syndrome is a rare condition in the general population (1/1000000) and is even less common during pregnancy. We report the case of a patient cared at 27 weeks of gestation (wg) for hypertension and electolyte disturbances. Cushing's syndrome was confirmed by salivary cortisol and ACTH assessment. RMN revealed a 9 cm left adrenal tumor. Severe hypertension and electolyte disturbances on the one hand, and diagnostic uncertainty on the other hand, imposed adrenalectomy at 29 wg. Twelve days later, fetal distress led to a caesarian section and birth of a well being male baby.

摘要

库欣综合征在普通人群中较为罕见(百万分之一),在孕期更为少见。我们报告一例在妊娠27周时因高血压和电解质紊乱接受治疗的患者。通过唾液皮质醇和促肾上腺皮质激素评估确诊为库欣综合征。磁共振成像显示左侧肾上腺有一个9厘米的肿瘤。一方面是严重的高血压和电解质紊乱,另一方面是诊断不确定,这使得在妊娠29周时进行了肾上腺切除术。十二天后,胎儿窘迫导致剖宫产,一名健康男婴出生。

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