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在德意志民主共和国和爱沙尼亚苏维埃社会主义共和国女性乳腺癌患者生存差异的背景下。

On the background of differences in survival of female breast cancer patients in the German Democratic Republic and the Estonian SSR.

作者信息

Aareleid T, Staneczek W, Rahu M, Möhner M

机构信息

Estonian Cancer Registry, Institute of Experimental and Clinical Medicine, Tallinn, Estonia, USSR.

出版信息

Neoplasma. 1990;37(5):587-94.

PMID:2234218
Abstract

The aim of this study was to describe the age-specific survival patterns and to analyse the differences between the survival rates of female breast cancer patients in the German Democratic Republic in 1976-1977 and the Estonian SSR in 1968-1981. The estimated 5-year relative survival rate (RSR) was 64.1% in the GDR and 55.9% in Estonia. Patients aged 55 years or older at diagnosis had higher survival in the GDR (5-year RSR 62.6%) than in Estonia (49.5%). That result was clearly connected with higher proportion of advanced tumors among older patients in Estonia. For patients younger than 55 years the difference of the 5-year RSR between the both countries was not statistically significant (GDR 65.3%, Estonia 63.4%). The standardization of overall 5-year RSR by stage and age, but also only by stage of the disease produced virtually equal results for the GDR and Estonia. It means that the main source of the differences in overall breast cancer survival rates between the GDR and Estonia are the discrepancies in stage distribution, particularly in older age groups.

摘要

本研究的目的是描述特定年龄的生存模式,并分析1976 - 1977年德意志民主共和国和1968 - 1981年爱沙尼亚苏维埃社会主义共和国女性乳腺癌患者生存率之间的差异。德意志民主共和国的估计5年相对生存率(RSR)为64.1%,爱沙尼亚为55.9%。诊断时年龄在55岁及以上的患者在德意志民主共和国的生存率(5年RSR为62.6%)高于爱沙尼亚(49.5%)。这一结果显然与爱沙尼亚老年患者中晚期肿瘤比例较高有关。对于年龄小于55岁的患者,两国之间5年RSR的差异无统计学意义(德意志民主共和国为65.3%,爱沙尼亚为63.4%)。按疾病分期和年龄对总体5年RSR进行标准化,或者仅按疾病分期进行标准化,德意志民主共和国和爱沙尼亚的结果几乎相同。这意味着德意志民主共和国和爱沙尼亚乳腺癌总体生存率差异的主要来源是分期分布的差异,特别是在老年人群体中。

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