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[小脑节细胞胶质瘤:一例报告]

[Cerebellar ganglioglioma: a case report].

作者信息

Kimura M, Suzuki M

机构信息

Department of Neurosurgery, Hirosaki University School of Medicine, Japan.

出版信息

No Shinkei Geka. 1990 Sep;18(9):861-5.

PMID:2234308
Abstract

A case of cerebellar ganglioglioma in a 5 year-old girl is presented. She came to our hospital on January 30, 1989 with complaints of headache of one year duration. CT scans disclosed a low density lesion suggesting a cystic tumor in the left cerebellar hemisphere with moderate hydrocephalus. Preoperative MRI demonstrated more clearly the location and extent of the tumor. She was operated on using suboccipital craniotomy, on March 3. Subtotal removal of the tumor was performed because the tumor had invaded the brain stem. She made an uneventful recovery without any neurological deficits. Histologically, the tumor was composed of ganglion cells and astrocytic cells, so it was diagnosed as ganglioglioma. Cerebellar ganglioglioma is a rare tumor, and only 17 cases have been reported including the present case. Clinical and radiological study of these cases revealed that there are no specific findings to indicate cerebellar ganglioglioma and preoperative diagnosis is impossible. But practically, MRI is the most sensitive method for identifying the extent of the lesion and, thus, is of benefit for deciding operative strategy.

摘要

本文报告一例5岁女孩的小脑节细胞胶质瘤。她于1989年1月30日因持续一年的头痛症状前来我院就诊。CT扫描显示低密度病变,提示左侧小脑半球有囊性肿瘤并伴有中度脑积水。术前MRI更清晰地显示了肿瘤的位置和范围。3月3日,她接受了枕下开颅手术。由于肿瘤侵犯脑干,故行肿瘤次全切除术。她术后恢复顺利,未出现任何神经功能缺损。组织学检查显示,肿瘤由神经节细胞和星形细胞组成,因此诊断为节细胞胶质瘤。小脑节细胞胶质瘤是一种罕见肿瘤,包括本病例在内仅报告过17例。对这些病例的临床和放射学研究表明,没有特定表现可提示小脑节细胞胶质瘤,术前诊断无法实现。但实际上,MRI是确定病变范围最敏感的方法,因此有助于决定手术策略。

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