Hunn Jessica, Rodriguez Gustavo C
Division of Gynecologic Oncology, NorthShore University Healthsystem, Department of Obstetrics and Gynecology, University of Chicago, Evanston, Illinois 60201, USA.
Clin Obstet Gynecol. 2012 Mar;55(1):3-23. doi: 10.1097/GRF.0b013e31824b4611.
Little is known regarding the early aspects of ovarian carcinogenesis. As a consequence, the identification of women at risk for the disease is based primarily on clinical grounds, with family history being the most important risk factor. In this review, we will discuss the various hypotheses regarding ovarian etiology and pathogenesis. In addition, we will discuss the epidemiology of ovarian cancer, including hereditary, reproductive, hormonal, inflammatory, dietary, surgical, and geographic factors that influence ovarian cancer risk.
关于卵巢癌发生的早期情况，人们所知甚少。因此，对患该疾病风险女性的识别主要基于临床依据，家族史是最重要的风险因素。在本综述中，我们将讨论关于卵巢癌病因和发病机制的各种假说。此外，我们还将讨论卵巢癌的流行病学，包括影响卵巢癌风险的遗传、生殖、激素、炎症、饮食、手术和地理因素。
Zotero 插件