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无酶信号放大的 DNA 酶传感器通过目标催化发夹组装。

Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly.

机构信息

The Key Lab of Analysis and Detection Technology for Food Safety of the MOE, College of Chemistry and Chemical Engineering, Fuzhou University, Fuzhou 350108, P. R. China.

出版信息

Chem Commun (Camb). 2012 Mar 25;48(25):3112-4. doi: 10.1039/c2cc30305a. Epub 2012 Feb 16.


DOI:10.1039/c2cc30305a
PMID:22343822
Abstract

A simple, highly sensitive and enzyme-free DNAzyme sensor based on target-catalyzed hairpin assembly is developed, which permits detection of 0.1 pM target DNA. Furthermore, this DNAzyme sensor is capable of detecting target DNA in real samples because of its high selectivity.

摘要

基于目标催化发夹组装,开发了一种简单、灵敏且无需酶的 DNAzyme 传感器,可检测到 0.1 pM 的目标 DNA。此外,由于其高选择性,这种 DNAzyme 传感器能够检测真实样品中的目标 DNA。

相似文献

[1]
Enzyme-free signal amplification in the DNAzyme sensor via target-catalyzed hairpin assembly.

Chem Commun (Camb). 2012-2-16

[2]
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[3]
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[8]
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[10]
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[9]
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