Garg P, Aggarwal P
Maharishi Markandeshwar Institute of Medical Sciences and Research, Mullana, Ambala, Haryana, India.
Nepal J Ophthalmol. 2012 Jan-Jun;4(1):150-61. doi: 10.3126/nepjoph.v4i1.5867.
Pregnancy is often associated with ocular changes which may be more commonly transient but occasionally, permanent. The ocular effects of pregnancy may be physiological or pathological or may be modifications of pre-existing conditions. Physiological changes include increased pigmentation around the cheeks, ptosis, changes in cornea and refractive status,decreased intraocular pressure. These usually resolve post partum. Pre-existing diseases such as Graves disease, Retinitis pigmentosa, optic neuritis, should be monitored due to their remission or relapses in pregnancy. There may be worsening of Diabetic retinopathy, and Central serous chorio-retinopathy with increased risk of Retinal detachment. Conditions like Glaucoma and Non infectious uveal inflammatory disorders may even improve transiently. Pre-eclampsia and eclampsia could result in hypertensive retinopathy, exudative retinal detachment and cortical blindness. Neuro-ophthalmological disorders such as venous sinus thrombosis, benign intracranial hypertension, pituitary adenoma, meningioma and optic neuritis should be kept in mind as differential diagnosis in pregnant women presenting with visual acuity loss, visual field loss, persistent headaches or oculomotor palsies. Use of ophthalmic drugs can affect fetal health during pregnancy.
妊娠常伴有眼部变化,这些变化通常较为常见的是短暂性的,但偶尔也会是永久性的。妊娠对眼部的影响可能是生理性的、病理性的,也可能是对原有病症的改变。生理变化包括脸颊周围色素沉着增加、上睑下垂、角膜和屈光状态改变、眼压降低。这些通常在产后消退。对于如格雷夫斯病、色素性视网膜炎、视神经炎等原有疾病,由于其在孕期可能缓解或复发,应予以监测。糖尿病视网膜病变和中心性浆液性脉络膜视网膜病变可能会加重,视网膜脱离风险增加。青光眼和非感染性葡萄膜炎症性疾病等情况甚至可能会暂时改善。子痫前期和子痫可导致高血压性视网膜病变、渗出性视网膜脱离和皮质盲。对于出现视力丧失、视野缺损、持续性头痛或动眼神经麻痹的孕妇,应考虑将神经眼科疾病如静脉窦血栓形成、良性颅内高压、垂体腺瘤、脑膜瘤和视神经炎作为鉴别诊断。孕期使用眼科药物会影响胎儿健康。