Chalam Kakarla V, Murthy Ravi K, Gupta Shailesh K, Khetpal Vijay
Department of Ophthalmology, College of Medicine, University of Florida, Jacksonville, Florida 32209, USA.
Eur J Ophthalmol. 2012 Sep-Oct;22(5):799-802. doi: 10.5301/ejo.5000115.
Pars plana vitrectomy with peeling of the internal limiting membrane is a well-established technique for the treatment of idiopathic macular holes with high success rates. Complications such as retinal tears may result from vitreous incarceration at the sclerotomy sites. Prophylactic laser retinopexy (LR) has recently been shown to decrease incidence of postvitrectomy rhegmatogenous retinal detachment but its efficacy in macular hole repair has not been established. In this study we evaluated the safety and efficacy of prophylactic LR and compared the patients to a control group that did not receive prophylactic treatment.
A retrospective, consecutive chart review was conducted comparing patients who underwent macular hole repair with LR to without LR. Patient demographics were collected and the number and time interval of retinal detachment in the 2 groups were compared. Statistical analysis was conducted between the 2 groups.
A total of 144 eyes underwent macular hole repair during the study period. A total of 76 eyes underwent LR and 68 eyes did not undergo LR. There were no significant differences in baseline characteristics between the 2 groups. At 1 year, RD occurred in 1 eye (1.31%) in the LR group and in 8 eyes (8.82%) without LR group (p<0.01).
Prophylactic LR decreases the incidence of postoperative retinal detachment a potentially disabling complication of macular hole repair surgery.
玻璃体切割联合内界膜剥除术是治疗特发性黄斑裂孔的一种成熟技术,成功率较高。巩膜切口处玻璃体嵌顿可能导致视网膜裂孔等并发症。预防性激光视网膜光凝术(LR)最近已被证明可降低玻璃体切除术后孔源性视网膜脱离的发生率,但其在黄斑裂孔修复中的疗效尚未确定。在本研究中,我们评估了预防性LR的安全性和有效性,并将患者与未接受预防性治疗的对照组进行了比较。
进行一项回顾性、连续病例分析,比较接受LR治疗和未接受LR治疗的黄斑裂孔修复患者。收集患者人口统计学资料,并比较两组视网膜脱离的数量和时间间隔。对两组进行统计学分析。
在研究期间,共有144只眼接受了黄斑裂孔修复。76只眼接受了LR治疗,68只眼未接受LR治疗。两组的基线特征无显著差异。1年后,LR组有1只眼(1.31%)发生视网膜脱离,未接受LR组有8只眼(8.82%)发生视网膜脱离(p<0.01)。
预防性LR可降低术后视网膜脱离的发生率,视网膜脱离是黄斑裂孔修复手术中一种可能导致残疾的并发症。