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A predictive model for progression of chronic kidney disease to kidney failure.慢性肾脏病进展为肾衰竭的预测模型。
JAMA. 2011 Apr 20;305(15):1553-9. doi: 10.1001/jama.2011.451. Epub 2011 Apr 11.
2
Barriers to timely arteriovenous fistula creation: a study of providers and patients.及时动静脉瘘管创建的障碍:对提供者和患者的研究。
Am J Kidney Dis. 2011 Jun;57(6):873-82. doi: 10.1053/j.ajkd.2010.12.020. Epub 2011 Mar 15.
3
Using proteinuria and estimated glomerular filtration rate to classify risk in patients with chronic kidney disease: a cohort study.利用蛋白尿和估计肾小球滤过率对慢性肾脏病患者进行风险分类:一项队列研究。
Ann Intern Med. 2011 Jan 4;154(1):12-21. doi: 10.7326/0003-4819-154-1-201101040-00003.
4
Using administrative datasets to study outcomes in dialysis patients: a validation study.利用行政数据集研究透析患者的结局:一项验证研究。
Med Care. 2010 Aug;48(8):745-50. doi: 10.1097/MLR.0b013e3181e419fd.
5
Relation between kidney function, proteinuria, and adverse outcomes.肾功能、蛋白尿与不良结局的关系。
JAMA. 2010 Feb 3;303(5):423-9. doi: 10.1001/jama.2010.39.
6
Outcomes of vascular access creation prior to dialysis: building the case for early referral.透析前血管通路建立的结果:支持早期转诊的依据
ASAIO J. 2009 Jul-Aug;55(4):355-60. doi: 10.1097/MAT.0b013e31819f635c.
7
Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.氯吡格雷对血液透析动静脉内瘘早期失功的影响:一项随机对照试验。
JAMA. 2008 May 14;299(18):2164-71. doi: 10.1001/jama.299.18.2164.
8
Hemodialysis arteriovenous fistula patency revisited: results of a prospective, multicenter initiative.重新审视血液透析动静脉内瘘通畅性:一项前瞻性多中心研究结果
Clin J Am Soc Nephrol. 2008 May;3(3):714-9. doi: 10.2215/CJN.02950707. Epub 2008 Feb 6.
9
EBPG on Vascular Access.血管通路的欧洲最佳实践指南
Nephrol Dial Transplant. 2007 May;22 Suppl 2:ii88-117. doi: 10.1093/ndt/gfm021.
10
When to refer patients with chronic kidney disease for vascular access surgery: should age be a consideration?慢性肾病患者何时应接受血管通路手术:年龄是否应作为一项考量因素?
Kidney Int. 2007 Mar;71(6):555-61. doi: 10.1038/sj.ki.5002078. Epub 2007 Jan 24.

瘘管建立后的起始透析概率。

Likelihood of starting dialysis after incident fistula creation.

机构信息

Departments of Medicine, University of Toronto, Ontario, Canada.

出版信息

Clin J Am Soc Nephrol. 2012 Mar;7(3):466-71. doi: 10.2215/CJN.08920811. Epub 2012 Feb 16.

DOI:10.2215/CJN.08920811
PMID:22344512
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3302676/
Abstract

BACKGROUND AND OBJECTIVES

Guidelines promote early fistula creation to avoid central venous catheter use. This practice may lead to fistula creations in patients who never receive dialysis. The objective of this study was to estimate the risk of fistula nonuse with long-term follow-up.

DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Administrative health data identified 1929 predialysis adults who had their first fistula creation between April of 2002 and March of 2006. Patients were followed for a minimum of 2 years or until they began dialysis, received a kidney transplant, or died.

RESULTS

The median follow-up times in patients who started dialysis, died without receiving dialysis, and remained in predialysis were 6.1, 11.5, and 38.7 months, respectively. Eighty-one percent of patients initiated dialysis; 9% of patients died without receiving dialysis, and 10% of patients remained predialysis. Forty percent of patients had their first fistula creation 3-12 months before initiating dialysis (the recommended window). Thirty percent were created within 90 days of starting dialysis; 30% were created more than 1 year before starting dialysis, and 10% were created more than 2 years before starting dialysis. Older patients, females, and patients with less comorbidity were not as likely to initiate dialysis after incident fistula creation.

CONCLUSIONS

Most patients who underwent fistula creation before starting dialysis eventually received dialysis with extended follow-up, but the risk was significantly modified by age, sex, and comorbidity. Many patients had fistula creations earlier or later than recommended.

摘要

背景和目的

指南提倡早期创建瘘管以避免使用中心静脉导管。这种做法可能会导致一些从未接受透析的患者进行瘘管创建。本研究的目的是在长期随访中评估瘘管未使用的风险。

设计、地点、参与者和测量:行政健康数据确定了 1929 名在 2002 年 4 月至 2006 年 3 月期间首次创建瘘管的透析前成年人。对患者进行了至少 2 年的随访,或直至他们开始透析、接受肾移植或死亡。

结果

开始透析、未接受透析而死亡和仍处于透析前状态的患者的中位随访时间分别为 6.1、11.5 和 38.7 个月。81%的患者开始透析;9%的患者未接受透析而死亡,10%的患者仍处于透析前状态。40%的患者在开始透析前 3-12 个月(推荐窗口)创建了第一个瘘管;30%在开始透析后 90 天内创建,30%在开始透析前 1 年以上创建,10%在开始透析前 2 年以上创建。年龄较大的患者、女性和合并症较少的患者在瘘管创建后开始透析的可能性较小。

结论

在开始透析前接受瘘管创建的大多数患者最终在延长随访后接受了透析,但年龄、性别和合并症显著改变了这种风险。许多患者的瘘管创建时间早于或晚于推荐时间。