Kojouri Ga, Aghajani E, Jahanabadi S, Kojouri A
Department of Clinical Sciences, School of Veterinary Medicine, Shahrekord University, Shahrekord, Iran.
Iran J Parasitol. 2011 Jun;6(2):17-22.
The role of minerals on parasite persistency and the interaction between minerals and animal responses to the parasite infestation is not clear. For these reasons, the present research was aimed to compare copper, zinc and iron status in sheep with parasitic myocarditis and healthy ones in 2009.
Blood and heart tissue samples were collected from 145 slaughtered sheep and histopathological findings were confirmed as myocardial sarcocystosis in 27 cases. Serum and tissue mineral level were determined by atomic absorption spectroscopy. Data were analyzed by Sigmastat program, using One Way Analysis of Variance (ANOVA) at the level of P<0.05.
Myocardial sarcocystosis significantly increase myocardial concentration of Cu, Zn and Fe (P<0.05).
These findings may explain the role of copper, zinc and iron in parasite persistency and may discuss the pathogenesis of sarcocystosis, which relates to evocate mentioned micronutrient to cardiac muscle.
矿物质在寄生虫持续性方面的作用以及矿物质与动物对寄生虫感染反应之间的相互作用尚不清楚。基于这些原因，本研究旨在比较2009年患有寄生虫性心肌炎的绵羊和健康绵羊的铜、锌和铁状况。
从145只屠宰绵羊中采集血液和心脏组织样本，27例组织病理学结果确诊为心肌肉孢子虫病。血清和组织矿物质水平通过原子吸收光谱法测定。数据采用Sigmastat程序进行分析，使用单向方差分析（ANOVA），P<0.05为差异有统计学意义。
心肌肉孢子虫病显著增加心肌中铜、锌和铁的浓度（P<0.05）。
这些发现可能解释了铜、锌和铁在寄生虫持续性中的作用，并可能探讨肉孢子虫病的发病机制，这与上述微量营养素对心肌的影响有关。
