Mainar Antoni Sicras, Artieda Ruth Navarro, Morillo Jesús Villoria, Escobar Ana Esquivias
Dirección de Planificación, Badalona Serveis Assistencials SA.
Clinicoecon Outcomes Res. 2012;4:39-47. doi: 10.2147/CEOR.S26116. Epub 2012 Jan 26.
The purpose of this study was to gather information about analgesic drug therapy in patients with chronic pain and perform cost estimates to guide future cost-effectiveness research in the area.
Data from patients aged 44 years and over suffering from any chronic condition and receiving regular analgesic drug therapy (for ≥6 months) who attended health care facilities within the area of Badalona during 2008 were collected in a retrospective study. Morbidity profiles were defined according to treatment setting (pain unit, hospital), World Health Organization analgesic step (1-2 versus 3), and a raw cost model based on resource use and work absenteeism was applied. Patients attending the pain unit or the hospital were considered undertreated if they were on step 1-2 analgesics. Multiple regression was used to compare costs between undertreated and non-undertreated patients among those attending the pain unit or the hospital.
Only 410 of 18,157 patients ascertained (2.3%) were on step 3 analgesics. Their direct costs were greater than those of patients on step 1-2 analgesics, although the opposite was true regarding indirect costs. Of patients seen in the pain unit and in the hospital, 2.3% and 20.1%, respectively, were considered undertreated. Regression analyses revealed even greater costs in the subgroup of undertreated patients.
Step 3 analgesics are barely used. Up to one-fifth of patients may be undertreated, generating greater costs than those considered to be properly treated. Regression analyses did not clarify the proportion of their cost excess that was attributable to undertreatment.
本研究的目的是收集有关慢性疼痛患者镇痛药物治疗的信息,并进行成本估算,以指导该领域未来的成本效益研究。
在一项回顾性研究中,收集了2008年期间在巴达洛纳地区医疗保健机构就诊的44岁及以上患有任何慢性疾病并接受常规镇痛药物治疗(≥6个月)的患者的数据。根据治疗环境(疼痛科、医院)、世界卫生组织镇痛阶梯(1-2级与3级)定义发病情况,并应用基于资源使用和旷工情况的原始成本模型。如果在疼痛科或医院就诊的患者使用1-2级镇痛药,则被视为治疗不足。使用多元回归比较疼痛科或医院就诊患者中治疗不足和非治疗不足患者之间的成本。
在确定的18157名患者中,只有410名(2.3%)患者使用3级镇痛药。他们的直接成本高于使用1-2级镇痛药的患者,尽管间接成本情况相反。在疼痛科和医院就诊的患者中,分别有2.3%和20.1%被认为治疗不足。回归分析显示,治疗不足患者亚组的成本更高。
3级镇痛药使用极少。高达五分之一的患者可能治疗不足,产生的成本高于那些被认为得到妥善治疗的患者。回归分析并未阐明其成本超支中归因于治疗不足的比例。