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[在经历缺氧的大鼠大脑中发育的移植物神经元的超微结构]

[The ultrastructure of the neurons of a graft developing in the brain of rats experiencing hypoxia].

作者信息

Cherkasova L V, Davletchina R F

出版信息

Ontogenez. 1990 Jul-Aug;21(4):395-402.

PMID:2234792
Abstract

Fragments of the brain cortex of 17- or 18-day-old rat embryos were allotransplanted into the brain cortex of rats subjected to hypoxia. Four days later the graft consisted of mixed differentiating neuroblasts. By the 100th to 130th day after transplantation the graft contained mature neurons, differentiating neurons and neuroblasts. Hypochromic neurons showing the signs of intracellular reparation were also detected. A well-developed neuropile was localized inside the graft. In contrast to the normal brain, neurons in the graft were not organized in layers.

摘要

将17或18日龄大鼠胚胎的大脑皮质碎片同种异体移植到缺氧大鼠的大脑皮质中。四天后,移植物由混合的分化成神经细胞组成。移植后第100至130天,移植物中含有成熟神经元、正在分化的神经元和成神经细胞。还检测到显示细胞内修复迹象的低色素神经元。移植物内部有发育良好的神经纤维网。与正常大脑不同,移植物中的神经元没有分层排列。

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