Department of Hematology, Catholic University, Rome, Italy.
Mediterr J Hematol Infect Dis. 2012;4(1):e2012008. doi: 10.4084/MJHID.2012.008. Epub 2012 Jan 25.
We describe the case of a 17- year old female who developed fatal haemophagocytic syndrome (HPS) one month following acute infection caused by Epstein-Barr virus (EBV). Despite initiation of treatment and reduction of EBV load, laboratory signs of HPS as severe cytopenia, hypofibrinogenemia, hyperferritinemia and hypertriglyceridemia persisted, and the patient died of multiorgan failure. HPS is a rare, but life-threatening complication of EBV infection.
我们描述了一例 17 岁女性的病例，她在 EBV（爱泼斯坦-巴尔病毒）急性感染一个月后发展为致命性噬血细胞综合征（HPS）。尽管开始了治疗并降低了 EBV 载量，但 HPS 的实验室迹象（严重血细胞减少症、低纤维蛋白原血症、高铁蛋白血症和高三酰甘油血症）仍然存在，患者死于多器官衰竭。HPS 是 EBV 感染的一种罕见但危及生命的并发症。
