Mirzayan M Javad, Klinge Petra M, Samii Madjid, Goetz Friedrich, Krauss Joachim K
Department of Neurosurgery, Medical School Hannover, Germany.
Br J Neurosurg. 2012 Jun;26(3):397-400. doi: 10.3109/02688697.2011.625060. Epub 2012 Feb 20.
Several new shunt technologies have been developed to optimize hydrocephalus treatment within the past few years. Overdrainage, however, still remains an unresolved problem. One new technology which may reduce the frequency of this complication is the use of a programmable shunt assistant (proSA). Inactive in a horizontal position, it impedes CSF flow in a vertical position according to a prescribed pressure level ranging from 0 to 40 cm H(2)O.
We exposed the proSA valve in an ex vivo protocol to MR systems operating at 3 and 7 Tesla to investigate its MRI safety.
Following 3 Tesla exposure, no changes in valve settings were noted. Adjustment to any pressure level was possible thereafter. The mean deflection angle was 23 ± 3°. After exposure to 7 Tesla, however, there were unintended pressure changes, and the mechanism for further adjustment of the valves even disintegrated.
According to the results of this study, proSA is safe with heteropolar vertical magnet alignment at 3 Tesla. Following 7 Tesla exposure, the valves lost their functional capability.
在过去几年中,已开发出几种新的分流技术以优化脑积水治疗。然而,引流过度仍然是一个未解决的问题。一种可能降低这种并发症发生率的新技术是使用可编程分流辅助装置(proSA)。它在水平位置不工作,而在垂直位置时,根据0至40 cm H₂O的规定压力水平阻碍脑脊液流动。
我们在体外实验方案中将proSA阀暴露于3特斯拉和7特斯拉运行的磁共振系统中,以研究其磁共振成像安全性。
在3特斯拉暴露后,未观察到阀门设置的变化。此后可以将其调整到任何压力水平。平均偏转角为23±3°。然而,在暴露于7特斯拉后,出现了意外的压力变化,甚至阀门进一步调节的机制也瓦解了。
根据本研究结果,proSA在3特斯拉异极垂直磁体排列下是安全的。在暴露于7特斯拉后,阀门失去了其功能能力。