Center for Research Methods and Data Analysis, University of Kansas, 1425 Jayhawk Blvd., Lawrence, KS 66045, USA.
Behav Genet. 2012 Jul;42(4):549-58. doi: 10.1007/s10519-012-9527-0. Epub 2012 Feb 15.
In previous work with a nationally representative sample of over 1,400 monozygotic and dizygotic twins born in the US, Tucker-Drob et al. (Psychological Science, 22, 125-133, 2011) uncovered a gene × environment interaction on scores on the Bayley Short Form test of mental ability (MA) at 2 years of age-higher socioeconomic status (SES) was associated not only with higher MA, but also with larger genetic contributions to individual differences in MA. The current study examined gene × SES interactions in mathematics skill and reading skill at 4 years of age (preschool age) in the same sample of twins, and further examined whether interactions detected at 4 years could be attributed to the persistence of the interaction previously observed at 2 years. For early mathematics skill but not early reading skill, genetic influences were more pronounced at higher levels of SES. This interaction was not accounted for by the interaction observed at 2 years. These findings indicate that SES moderates the etiological influences on certain cognitive functions at multiple stages of child development.
在之前的研究中,Tucker-Drob 等人使用一个超过 1400 对美国出生的同卵和异卵双胞胎的全国代表性样本,在心理科学杂志(22,125-133,2011)上揭示了一个在 2 岁时的贝利简短形式心理能力测试(MA)分数上的基因-环境交互作用——较高的社会经济地位(SES)不仅与较高的 MA 相关,而且与 MA 个体差异的更大遗传贡献相关。本研究在相同的双胞胎样本中,检查了 4 岁(学前年龄)时的数学技能和阅读技能上的基因-SES 交互作用,并进一步探讨了在 4 岁时检测到的交互作用是否可以归因于之前在 2 岁时观察到的交互作用的持续性。对于早期数学技能,但不是早期阅读技能,遗传影响在 SES 较高水平时更为明显。这种交互作用不能用在 2 岁时观察到的交互作用来解释。这些发现表明,SES 在儿童发展的多个阶段调节着某些认知功能的病因影响。