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Primary skin fibroblasts as a model of Parkinson's disease.
Mol Neurobiol. 2012 Aug;46(1):20-7. doi: 10.1007/s12035-012-8245-1. Epub 2012 Feb 19.
2
LRRK2 Expression Is Deregulated in Fibroblasts and Neurons from Parkinson Patients with Mutations in PINK1.
Mol Neurobiol. 2018 Jan;55(1):506-516. doi: 10.1007/s12035-016-0303-7. Epub 2016 Dec 14.
3
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.
Nature. 2006 Jun 29;441(7097):1162-6. doi: 10.1038/nature04779. Epub 2006 May 3.
4
Parkinson patient fibroblasts show increased alpha-synuclein expression.
Exp Neurol. 2008 Aug;212(2):307-13. doi: 10.1016/j.expneurol.2008.04.004. Epub 2008 Apr 16.
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Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress.
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Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition.
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10
Bioenergetic and proteolytic defects in fibroblasts from patients with sporadic Parkinson's disease.
Biochim Biophys Acta. 2014 Sep;1842(9):1385-94. doi: 10.1016/j.bbadis.2014.05.008. Epub 2014 May 20.

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Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis.
Acta Neuropathol Commun. 2025 Feb 21;13(1):38. doi: 10.1186/s40478-025-01933-0.
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Multi-Omics Approach Reveals Genes and Pathways Affected in Miller-Dieker Syndrome.
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1
Restriction of trophic factors and nutrients induces PARKIN expression.
Neurogenetics. 2012 Feb;13(1):9-21. doi: 10.1007/s10048-011-0303-8. Epub 2011 Oct 26.
2
Copy number variation and selection during reprogramming to pluripotency.
Nature. 2011 Mar 3;471(7336):58-62. doi: 10.1038/nature09871.
3
Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases.
Hum Mol Genet. 2011 Mar 15;20(6):1074-83. doi: 10.1093/hmg/ddq550. Epub 2010 Dec 21.
4
Oxidative stress in skin fibroblasts cultures from patients with Parkinson's disease.
BMC Neurol. 2010 Oct 19;10:95. doi: 10.1186/1471-2377-10-95.
5
Mutant Parkin impairs mitochondrial function and morphology in human fibroblasts.
PLoS One. 2010 Sep 27;5(9):e12962. doi: 10.1371/journal.pone.0012962.
6
Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects.
Neurobiol Dis. 2011 Jan;41(1):111-8. doi: 10.1016/j.nbd.2010.08.027. Epub 2010 Sep 15.
8
Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells.
Biochem Biophys Res Commun. 2010 Aug 27;399(3):331-5. doi: 10.1016/j.bbrc.2010.07.033. Epub 2010 Jul 15.
10
Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients.
Hum Mol Genet. 2010 Aug 15;19(16):3124-37. doi: 10.1093/hmg/ddq215. Epub 2010 May 27.

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