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关节炎患者的功能障碍在性别上的差异:疾病持续时间和合并症的作用。

Gender differences in functional limitations among Canadians with arthritis: the role of disease duration and comorbidity.

机构信息

Health Analysis Division at Statistics Canada, Ottawa, Ontario K1A 0T6.

出版信息

Health Rep. 2011 Dec;22(4):7-14.

PMID:22352147
Abstract

BACKGROUND

Mechanisms underlying gender disparities in functional limitations among people with arthritis remain unclear. This study examined gender differences in the relationship between disease duration and comorbidity and functional limitations among people with arthritis.

DATA AND METHODS

Data were from the arthritis component of the 2009 Survey on Living with Chronic Diseases in Canada. People were considered to have functional limitations if they reported that arthritis limits them "a lot" in activities of daily living. Those with no functional limitations were the reference group. Gender-stratified weighted multivariate binary logistic regression analyses were conducted.

RESULTS

In a fully adjusted multivariate analysis, only among women was time elapsed since the arthritis diagnosis associated with functional limitations. Disabling and life-threatening chronic conditions were associated with functional limitations in both genders. Among men, obesity and low household income were associated with higher odds of functional limitations, while living in British Columbia was associated with decreased odds. For women, smoking, not engaging in physical activity, residing in a non-Atlantic province, and having excess weight increased the odds of functional limitations, while habitual alcohol drinking decreased the odds.

INTERPRETATION

Gender differences in the risks of reporting functional limitations were significant. These differences appear to be driven by duration of having arthritis, and disparities in health behavioural factors, household income and region of residence. The association between chronic conditions and functional limitations was similar for men and women.

摘要

背景

关节炎患者中功能障碍的性别差异的潜在机制仍不清楚。本研究考察了关节炎患者中疾病持续时间和合并症与功能障碍之间的关系的性别差异。

数据和方法

数据来自加拿大 2009 年慢性疾病生活状况调查的关节炎部分。如果人们报告关节炎“严重”限制了他们的日常生活活动,那么他们就被认为存在功能障碍。没有功能障碍的人作为参考组。进行了性别分层加权多元二项逻辑回归分析。

结果

在完全调整后的多元分析中,只有女性关节炎诊断后的时间与功能障碍相关。致残和危及生命的慢性疾病与两性的功能障碍相关。在男性中,肥胖和低收入家庭与更高的功能障碍几率相关,而居住在不列颠哥伦比亚省则与较低的几率相关。对于女性来说,吸烟、不进行体育活动、居住在非大西洋省份以及超重会增加功能障碍的几率,而习惯性饮酒则会降低几率。

解释

报告功能障碍的风险存在显著的性别差异。这些差异似乎是由关节炎的持续时间以及健康行为因素、家庭收入和居住地区的差异驱动的。慢性疾病与功能障碍之间的关联在男性和女性中相似。

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