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表现为卒中的多形性胶质母细胞瘤:一例电生理及临床病理病例报告

Glioblastoma multiforme presenting as stroke: an electrophysiological and clinicopathological case report.

作者信息

Kaplan P E, Santana R, Cohen J, Leestma J

出版信息

Arch Phys Med Rehabil. 1979 Feb;60(2):74-7.

PMID:223522
Abstract

A 55-year-old man having hemiplegia after the sudden onset of a stroke was referred for rehabilitation. Cerebral angiography had demonstrated occlusion of the left middle cerebral artery and steroid therapy had been started. Attempted tapering of the steroid therapy on admission for rehabilitation resulted in the patient having severe headaches and confusion. Blink reflex evaluation, somatosensory cerebral evoked potential determinations and visual evoked responses were all consistent with a widespread process involving the parietal lobe of the patient's left cerebral hemisphere. Computerized axial tomography indicated an abnormality consistent with a space-occupying lesion. Craniotomy revealed the presence of a glioblastoma multiforme in the left cerebral hemisphere. Electrodiagnostic evaluation was entirely consistent with the operative finding of widespread involvement of the patient's left parietal lobe. Stroke patients whose conditions deteriorate over time must be serially evaluated in order to determine possible other causes of their symptoms.

摘要

一名55岁男性,中风突发后出现偏瘫,被转诊至康复科。脑血管造影显示左大脑中动脉闭塞,已开始使用类固醇治疗。康复入院时尝试逐渐减少类固醇治疗剂量,结果导致患者出现严重头痛和意识模糊。眨眼反射评估、体感脑诱发电位测定和视觉诱发电位均与患者左大脑半球顶叶广泛受累的过程一致。计算机断层扫描显示存在与占位性病变相符的异常。开颅手术发现左大脑半球存在多形性胶质母细胞瘤。电诊断评估与手术发现的患者左顶叶广泛受累完全一致。随着时间推移病情恶化的中风患者必须进行系列评估,以确定其症状可能的其他原因。

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