Nambu T, Yoshikawa H, Shirato H, Suzuki K
Department of Radiology, Obihiro Kosei Hospital.
Nihon Igaku Hoshasen Gakkai Zasshi. 1990 Aug 25;50(8):1019-21.
A prospective study of late adverse reactions of non-ionic intravenous contrast media was performed. Information was collected from questionnaires returned by the patients, and also from further interviews. The incidence of adverse reactions was 8.3% in all patients, and was higher in female (11.1%) than male (5.8%). They were more frequent in the patients with age ranging from 20 to 49 than those older than 50. The most frequent symptom was headache, followed by itching, skin rashes, nausea, dizziness, and general fatigue. More than half of the reactions occurred within six hours after injection, but reactions a few days later were also reported.
对非离子型静脉造影剂的迟发不良反应进行了一项前瞻性研究。信息收集自患者返回的问卷，以及进一步的访谈。所有患者中不良反应的发生率为8.3%，女性（11.1%）高于男性（5.8%）。年龄在20至49岁的患者比50岁以上的患者更频繁出现不良反应。最常见的症状是头痛，其次是瘙痒、皮疹、恶心、头晕和全身乏力。超过一半的反应发生在注射后6小时内，但也有几天后出现反应的报告。
