Barut Aykut, Arikan Iker, Harma Muge, Harma Mehmeet Ibrahim, Barut Figen, Coskan Ahmet
Department of Gynecology and Obstetrics, Zonguldak Karaelmas University, Zonguldak, Turkey.
J Pak Med Assoc. 2011 Oct;61(10):1016-7.
Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pregnancy. Here, we describe the case of a recurrent partial hydatidiform mole after an initial healthy pregnancy. Both pregnancies were evacuated by suction curettage, and the patient was followed by serial monitoring of beta-human chorionic gonadotropin levels. Recurrent molar pregnancy is not an indication for chemotherapy, and subsequent pregnancies do not have an increased risk for other obstetric complications.
葡萄胎是一种异常妊娠,其特征为非典型增生的滋养层细胞和水肿绒毛。其发生率约为每1000次妊娠中有1例。葡萄胎的复发风险在随后的妊娠中约为60分之一,在第三次妊娠中约为6.5分之一。在复发的病例中,大多数葡萄胎与前次妊娠的类型相同。在此,我们描述一例在首次健康妊娠后复发的部分性葡萄胎病例。两次妊娠均通过吸刮术终止,患者随后接受了β-人绒毛膜促性腺激素水平的系列监测。复发性葡萄胎妊娠并非化疗指征,且随后的妊娠发生其他产科并发症的风险并未增加。