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复发性部分性葡萄胎

Recurrent partial hydatidiform mole.

作者信息

Barut Aykut, Arikan Iker, Harma Muge, Harma Mehmeet Ibrahim, Barut Figen, Coskan Ahmet

机构信息

Department of Gynecology and Obstetrics, Zonguldak Karaelmas University, Zonguldak, Turkey.

出版信息

J Pak Med Assoc. 2011 Oct;61(10):1016-7.

Abstract

Hydatidiform moles are abnormal conceptions characterised by atypical hyperplastic trophoblasts and hydropic villi. Their incidence is approximately 1 in 1000 pregnancies. The recurrence risk of hydatidiform mole is approximately 1 in 60 in a subsequent pregnancy and 1 in 6.5 in the third pregnancy. In cases with recurrence, the majority of moles are of the same type as that in the preceding pregnancy. Here, we describe the case of a recurrent partial hydatidiform mole after an initial healthy pregnancy. Both pregnancies were evacuated by suction curettage, and the patient was followed by serial monitoring of beta-human chorionic gonadotropin levels. Recurrent molar pregnancy is not an indication for chemotherapy, and subsequent pregnancies do not have an increased risk for other obstetric complications.

摘要

葡萄胎是一种异常妊娠,其特征为非典型增生的滋养层细胞和水肿绒毛。其发生率约为每1000次妊娠中有1例。葡萄胎的复发风险在随后的妊娠中约为60分之一,在第三次妊娠中约为6.5分之一。在复发的病例中,大多数葡萄胎与前次妊娠的类型相同。在此,我们描述一例在首次健康妊娠后复发的部分性葡萄胎病例。两次妊娠均通过吸刮术终止,患者随后接受了β-人绒毛膜促性腺激素水平的系列监测。复发性葡萄胎妊娠并非化疗指征,且随后的妊娠发生其他产科并发症的风险并未增加。

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