Sheikh Adil, Faisal Syed Shah, Jabbar Abdul
Department of Medicine, Aga Khan University, Karachi.
J Pak Med Assoc. 2011 Oct;61(10):1037-41.
To find the frequency of silent myocardial ischaemia in diabetics as compared to non-diabetics.
This was a cross sectional study conducted between November 2008 and March 2010. Two hundred subjects were recruited by convenience sampling after informed consent. All were subjected to an exercise stress test. Electrocardiographic changes were noted for silent Ischaemia Descriptive Statistics were applied for significance.
Of the 200 subjects included in the study, 31 had diabetes and 1 69 were non-diabetics. The mean age was 46 +/- 10 years. Twenty eight subjects tested positive for silent ischaemia, of whom six were diabetics (19%) and 22 were non-diabetics (13%). Hypertension and obesity were found more frequently in diabetics (48% Vs 27%) p = 0.019 and (35% Vs 18%) p = 0.027 respectively. Despite the greater proportion of diabetics having asymptomatic myocardial ischaemia as compared to nondiabetics statistical significance (p = 0.397) was not observed.
There was no significant difference in the frequency of silent ischaemia amongst the two groups.
比较糖尿病患者与非糖尿病患者无症状性心肌缺血的发生率。
这是一项于2008年11月至2010年3月期间开展的横断面研究。在获得知情同意后，通过便利抽样招募了200名受试者。所有受试者均接受运动负荷试验。记录心电图变化以确定无症状性缺血情况。应用描述性统计分析其显著性。
在纳入研究的200名受试者中，31名患有糖尿病，169名是非糖尿病患者。平均年龄为46±10岁。28名受试者无症状性缺血检测呈阳性，其中6名是糖尿病患者（19%），22名是非糖尿病患者（13%）。糖尿病患者中高血压和肥胖的发生率更高（分别为48%对27%，p = 0.019；35%对18%，p = 0.027）。尽管与非糖尿病患者相比，糖尿病患者中无症状性心肌缺血的比例更高，但未观察到统计学显著性（p = 0.397）。
两组之间无症状性缺血的发生率无显著差异。
