Birmingham/Atlanta GRECC, Atlanta VA Medical Center, Decatur, GA, USA.
Int J Clin Pract. 2012 Apr;66(4):369-73. doi: 10.1111/j.1742-1241.2011.02868.x. Epub 2012 Feb 22.
The aim of this study was to evaluate if men with varying degrees of bother from a similar number of nocturia episodes differ with respect to self-rated sleep characteristics and fatigue.
As part of the baseline assessments during a nocturia treatment trial, 55 participants reported frequency and bother of nocturia using the AUA Symptom Inventory and completed 7-day sleep diaries prior to treatment. Participants who reported moderate nocturia (either two or three episodes nightly) were further grouped into categories of LOW (nocturia is no problem or a very small problem) or HIGH bother (nocturia is a big problem). Information from the participant completed sleep diaries was abstracted, including information on daytime napping, total sleep time, mean time needed to return to sleep, nighttime ratings of fatigue, and daytime ratings of fatigue.
Of the 55 individuals who completed the pilot study, 24 study participants reported two or three episodes of nocturia and had either HIGH (n = 11) or LOW (n = 13) bother. Participants categorised with HIGH bother were significantly more likely than those with LOW bother to report difficulty initiating sleep (47.7 ± 34.4 vs. 23.5 ± 13.6 min, p = 0.05), difficulty returning to sleep after an awakening (28.9 ± 16.1 vs. 15.4 ± 9.6 min, p = 0.03) and greater morning fatigue (3.3 ± 0.7 vs. 2.5 ± 1.0, p = 0.04 on a 7-point scale).
Since bother related to nocturia is linked to sleep quality, interventions targeting fatigue and sleep maintenance may provide useful targets in the management of nocturia in men.
本研究旨在评估夜间排尿次数相似但困扰程度不同的男性在自我评估的睡眠特征和疲劳方面是否存在差异。
作为夜间遗尿症治疗试验基线评估的一部分，55 名参与者使用 AUA 症状量表报告夜间排尿频率和困扰程度，并在治疗前完成 7 天睡眠日记。报告中度夜间遗尿症（每晚两次或三次）的参与者进一步分为低（夜间遗尿症不是问题或只是很小的问题）或高（夜间遗尿症是大问题）困扰组。从参与者完成的睡眠日记中提取信息，包括白天小睡、总睡眠时间、平均入睡时间、夜间疲劳评分和白天疲劳评分。
在完成该初步研究的 55 名个体中，有 24 名参与者报告夜间排尿次数为两次或三次，且有高（n=11）或低（n=13）困扰。与低困扰组相比，高困扰组参与者更有可能报告入睡困难（47.7±34.4 与 23.5±13.6 分钟，p=0.05）、觉醒后难以再次入睡（28.9±16.1 与 15.4±9.6 分钟，p=0.03）和早晨疲劳感更强烈（3.3±0.7 与 2.5±1.0，p=0.04，在 7 分制上）。
由于与夜间遗尿症相关的困扰与睡眠质量有关，针对疲劳和睡眠维持的干预措施可能是男性夜间遗尿症管理的有效目标。
