Norman Consulting, 18 Pink Lane, Burnham, Bucks SL1 8JW, UK.
Expert Opin Ther Pat. 2012 Mar;22(3):335-9. doi: 10.1517/13543776.2012.665878. Epub 2012 Feb 23.
A small number of novel 7-(1-alkylpyrazol-4-yl)-N-[(4-fluoro-4-piperidyl)methyl]-1,6-naphthyridin-5-amines are claimed. The compounds are Syk kinase inhibitors useful in the treatment of allergic and inflammatory diseases and cancer. They represent another possible development candidate in what has become an increasing area of activity in the search for kinase inhibitors for the treatment of chronic diseases.
要求提供少量新型 7-(1-烷基吡唑-4-基)-N-[(4-氟-4-哌啶基)甲基]-1,6-萘啶-5-胺。这些化合物是 Syk 激酶抑制剂，可用于治疗过敏和炎症性疾病以及癌症。它们是在寻找用于治疗慢性疾病的激酶抑制剂的日益活跃的领域中，另一个有潜力的候选药物。
