Reges Ricardo Vieira, Vicente Walter Vilella de Andrade, Rodrigues Alfredo José, Basseto Solange, Alves Junior Lafaiete, Scorzoni Filho Adilson, Ferreira César Augusto, Évora Paulo Roberto Barbosa
Division of Thoracic and Cardiovascular Surgery, Department of Anatomy, Faculty of Medicine of Ribeirão Preto, Universidade de São Paulo, SP, Brazil.
Rev Bras Cir Cardiovasc. 2011 Oct-Dec;26(4):609-16. doi: 10.5935/1678-9741.20110052.
Retrograde autologous priming (RAP) is a cardiopulmonary bypass (CPB) method, at low cost. Previous studies have shown that this method reduces hemodilution and blood transfusions needs through increased intra-operative hematocrit.
To evaluate RAP method, in relation to standard CPB (crystalloid priming), in adult patients.
Sixty-two patients were randomly allocated to two groups: 1) Group RAP (n = 27) of patients operated using the RAP and; 2) Control group of patients operated using CPB standard crystalloid method (n = 35). The RAP was performed by draining crystalloid prime from the arterial and venous lines, before CPB, into a collect recycling bag. The main parameters analyzed were: 1) CPB hemodynamic data; 2) Hematocrit and hemoglobin values; 3) The need for blood transfusions.
It was observed statistically significant fewer transfusions during surgery and reduced CPB hemodilution using RAP. The CPB hemodynamic values were similar, observing a tendency to use lower CPB flows in the RAP group patients.
This investigation was designed to be a small-scale pilot study to evaluate the effects of RAP, which were demonstrated concerning the CPB hemodilution and blood transfusions.
逆行自体预充（RAP）是一种成本较低的体外循环（CPB）方法。先前的研究表明，该方法通过提高术中血细胞比容来减少血液稀释和输血需求。
评估RAP方法在成年患者中相对于标准CPB（晶体预充）的效果。
62例患者被随机分为两组：1）采用RAP进行手术的患者RAP组（n = 27）；2）采用CPB标准晶体方法进行手术的患者对照组（n = 35）。RAP通过在CPB前将动脉和静脉管路中的晶体预充液引流到一个收集回收袋中来进行。分析的主要参数包括：1）CPB血流动力学数据；2）血细胞比容和血红蛋白值；3）输血需求。
观察到使用RAP时手术期间的输血次数在统计学上显著减少，且CPB血液稀释程度降低。CPB血流动力学值相似，观察到RAP组患者有使用较低CPB流量的趋势。
本研究设计为一项小规模的试点研究，以评估RAP的效果，结果表明其在CPB血液稀释和输血方面具有优势。
