Universidade Federal de Pernambuco, Recife, PE, Brazil.
Braz J Infect Dis. 2012 Jan-Feb;16(1):1-8. doi: 10.1016/s1413-8670(12)70266-0.
The incidence of ischemic heart disease is higher in patients with HIV/AIDS. However, the frequency of angina pectoris in these patients is still not known. Literature about this subject is still scarce.
To evaluate the prevalence of angina pectoris and risk factors for coronary disease and to examine the association between traditional risk factors and HIV-related risk factors and angina pectoris.
An epidemiological cross-sectional study, analyzed as case-control study, involving 584 patients with HIV/AIDS. Angina pectoris was identified by Rose questionnaire, classified as definite or possible. Information regarding risk factors was obtained through a questionnaire, biochemical laboratory tests, medical records and anthropometric measures taken during consultations at AIDS treatment clinics in Pernambuco, Brazil, from June 2007 to February 2008. To adjust the effect of each factor in relation to others, multiple logistic regression was used.
There was a preponderance of men (63.2%); mean ages were 39.8 years for men, 36.8 years for women. The prevalence of definite and possible angina were 11% and 9.4%, respectively, totaling 20.4%, with independent associations between angina and smoking (OR = 2.88; 95% CI: 1.69-4.90), obesity (OR = 1.62; 95% CI: 0.97-2.70), family history of heart attack (OR = 1.70; 95% CI: 1.00-2.88), low schooling (OR = 2.11; 95% CI: 1.24-3.59), and low monthly income (OR = 2.93; 95% CI: 1.18-7.22), even after adjustment for age.
This study suggests that angina pectoris is underdiagnosed, even in patients with medical monitoring, revealing lost opportunities in identification and prevention of cardiovascular morbidity.
HIV/AIDS 患者的缺血性心脏病发病率较高。然而，这些患者心绞痛的频率尚不清楚。关于这个主题的文献仍然很少。
评估心绞痛的患病率和冠心病的危险因素，并研究传统危险因素与 HIV 相关危险因素和心绞痛之间的关系。
这是一项流行病学的横断面研究，分析为病例对照研究，涉及 584 名 HIV/AIDS 患者。心绞痛通过 Rose 问卷确定，分为明确或可能。通过问卷、生化实验室检查、病历和巴西伯南布哥州艾滋病治疗诊所就诊时的人体测量数据获得有关危险因素的信息，时间为 2007 年 6 月至 2008 年 2 月。为了调整每个因素与其他因素的关系，使用多变量逻辑回归。
男性居多（63.2%）；男性平均年龄为 39.8 岁，女性平均年龄为 36.8 岁。明确和可能的心绞痛患病率分别为 11%和 9.4%，总患病率为 20.4%，心绞痛与吸烟（OR=2.88；95%CI：1.69-4.90）、肥胖（OR=1.62；95%CI：0.97-2.70）、心脏病家族史（OR=1.70；95%CI：1.00-2.88）、低教育程度（OR=2.11；95%CI：1.24-3.59）和低月收入（OR=2.93；95%CI：1.18-7.22）独立相关，即使在调整年龄后也是如此。
本研究表明，即使在接受医疗监测的患者中，心绞痛也被漏诊，这表明在识别和预防心血管发病率方面错失了机会。
