Robinzon B, Rozenboim I, Arnon E, Snapir N
Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
Poult Sci. 1990 Jul;69(7):1220-2. doi: 10.3382/ps.0691220.
Tamoxifen (TAM) is an antiestrogen that advances sexual puberty in cockerels, turkey toms, and Muscovy drakes. The effect of TAM on semen-fertilization capacity in White Leghorn (WL) male chicks was assayed in the present study. Sixty, 2-wk-old, male chicks were divided into two equal groups. The chicks from one group were injected im with 1 mg of TAM per kg of BW every other day; those from the second group were vehicle-treated (with corn oil) and served as controls. Each chick was paired with a virgin, WL laying hen. When semen was produced, the paired female was inseminated twice a week. The results revealed that TAM administration caused the early production of fertile semen, which resulted in the first normal descendants as early as 8 wk of age and brought about 100% of parenthood by the age of 88 days.
他莫昔芬（TAM）是一种抗雌激素药物，可使小公鸡、雄火鸡和番鸭性早熟。本研究测定了TAM对白来航（WL）雄性雏鸡精液受精能力的影响。60只2周龄雄性雏鸡被平均分为两组。一组雏鸡每隔一天腹腔注射每千克体重1毫克的TAM；另一组雏鸡接受载体处理（玉米油）作为对照。每只雏鸡与一只未交配过的WL产蛋母鸡配对。当产生精液时，每周给配对的母鸡输精两次。结果显示，给予TAM可使精液提前产生并具有受精能力，最早在8周龄时就能产生第一批正常后代，到88日龄时育雏成功率达到100%。
