Institute of General Pathology, University of Genoa, Via L.B. Alberti 2, 16132, Genoa, Italy.
Cytotechnology. 1993 Jan;11(Suppl 1):S126-9. doi: 10.1007/BF00746076.
In conclusion, hepatoma cell lines displaying multiple combinations of bioactivating and inactivating enzymes, even if do not seem to represent liver-specific bio-indicators of toxicity, are a polyvalent liver system, suitable to evaluate particular end-points.
总之,表现出多种生物激活和失活酶组合的肝癌细胞系,即使似乎不能代表肝脏毒性的特异性生物标志物,也是一种多效性的肝脏系统,适合评估特定的终点。