艰难梭菌毒素 A 的作用模式：一项体外研究。
On the mode of action ofClostridium difficile toxin A: anin vitro study.
机构信息
Lab. Ultrastrutture, Istituto Superiore di Sanita', Viale Regina Elena 299, 00161, Roma, Italy.
出版信息
Cytotechnology. 1991 Feb;5(Suppl 1):84-5. doi: 10.1007/BF00736818.
PMID:22358964
Abstract
C. difficile toxin A causes the rounding up and the formation of surface blebs in normal rat intestinal crypt cells (IEC-6). These phenomena, together with the inhibition of DNA synthesis and the cell lysis, could be the mechanisms leading the toxin-treated cells to death.
摘要
艰难梭菌毒素 A 导致正常大鼠肠隐窝细胞（IEC-6）的圆形化和表面疱的形成。这些现象，以及 DNA 合成的抑制和细胞裂解，可能是导致毒素处理细胞死亡的机制。
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