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Long-term culture of human LAK cells.

作者信息

Testa U, Montesoro E, Bulgarini D, Isacchi G, Mastroberardino G, Calabresi F, Peschle C

机构信息

Department of Hematology-Oncology, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161, Rome, Italy.

出版信息

Cytotechnology. 1991 Feb;5(Suppl 1):139-40. doi: 10.1007/BF00736833.

DOI:10.1007/BF00736833
PMID:22358979
Abstract
摘要

相似文献

1
Long-term culture of human LAK cells.人淋巴因子激活的杀伤细胞的长期培养
Cytotechnology. 1991 Feb;5(Suppl 1):139-40. doi: 10.1007/BF00736833.
2
Lymphokine-activated killer activity in long-term cultures with anti-CD3 plus interleukin 2: identification and isolation of effector subsets.在抗CD3加白细胞介素2的长期培养中淋巴细胞激活的杀伤活性：效应子亚群的鉴定与分离
Cancer Res. 1989 Feb 15;49(4):963-8.
3
A high density cell culture system for generation of human lymphokine-activated killer (LAK) cells for clinical use in adoptive immunotherapy.一种用于生成人淋巴因子激活的杀伤（LAK）细胞的高密度细胞培养系统，用于过继性免疫治疗的临床应用。
J Clin Lab Immunol. 1990 May;32(1):41-7.
4
Long-term growth of lymphokine-activated killer (LAK) cells: role of anti-CD3, beta-IL 1, interferon-gamma and -beta.淋巴因子激活的杀伤细胞（LAK）的长期生长：抗CD3、β-白细胞介素-1、干扰素-γ和-β的作用
J Immunol. 1987 Apr 15;138(8):2728-33.
5
Sequential TNF and TGF-beta regulation of expansion and induction of cytotoxicity in long-term cultures of lymphokine-activated killer cells.在淋巴因子激活的杀伤细胞长期培养中，肿瘤坏死因子（TNF）和转化生长因子-β（TGF-β）对细胞扩增及细胞毒性诱导的顺序调节
Lymphokine Cytokine Res. 1994 Apr;13(2):139-45.
6
Heterogeneity of long-term cultured activated killer cells induced by anti-T3 antibody.抗T3抗体诱导的长期培养活化杀伤细胞的异质性
J Immunol. 1988 Aug 15;141(4):1390-7.
7
Interleukin-15 supports generation of highly potent clinical-grade natural killer cells in long-term cultures for targeting hematological malignancies.白细胞介素-15 在长期培养中支持生成高效的临床级自然杀伤细胞，用于靶向血液系统恶性肿瘤。
Exp Hematol. 2011 Sep;39(9):904-14. doi: 10.1016/j.exphem.2011.06.003. Epub 2011 Jun 13.
8
Infiltration patterns of short- and long-term cultured A-NK and T-LAK cells following adoptive immunotherapy.过继免疫治疗后短期和长期培养的A-NK细胞及T-LAK细胞的浸润模式
Scand J Immunol. 1998 Jun;47(6):532-40. doi: 10.1046/j.1365-3083.1998.00339.x.
9
Lymphokine-activated killer cells: culture conditions for the generation of maximal in vitro cytotoxicity in cells from normal donors.
Cancer Res. 1987 Oct 15;47(20):5504-8.
10
Lymphokine-activated killer (LAK) cells from human intestinal mucosa: cytotoxic activity against tumor cell lines and modified self but not autologous and allogeneic colon cancer cells.
J Surg Res. 1988 Apr;44(4):445-54. doi: 10.1016/0022-4804(88)90188-6.

本文引用的文献

1
Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells.淋巴因子激活的杀伤细胞现象。II. 前体细胞表型在血清学上与外周T淋巴细胞、记忆性细胞毒性胸腺来源淋巴细胞及自然杀伤细胞不同。
J Exp Med. 1983 Mar 1;157(3):884-97. doi: 10.1084/jem.157.3.884.
2
Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.淋巴因子激活的杀伤细胞现象。白细胞介素2激活的自体人外周血淋巴细胞对天然杀伤抗性新鲜实体瘤细胞的杀伤作用。
J Exp Med. 1982 Jun 1;155(6):1823-41. doi: 10.1084/jem.155.6.1823.
3
Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer.
对转移性癌症患者进行自体淋巴因子激活的杀伤细胞和重组白细胞介素-2全身给药的观察。
N Engl J Med. 1985 Dec 5;313(23):1485-92. doi: 10.1056/NEJM198512053132327.
4
Recombinant interleukin 2 stimulates in vivo proliferation of adoptively transferred lymphokine-activated killer (LAK) cells.重组白细胞介素2刺激过继转移的淋巴因子激活的杀伤细胞（LAK细胞）在体内增殖。
J Immunol. 1985 Nov;135(5):3623-35.
5
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone.关于使用淋巴因子激活的杀伤细胞和白细胞介素-2或单独使用高剂量白细胞介素-2治疗157例晚期癌症患者的进展报告。
N Engl J Med. 1987 Apr 9;316(15):889-97. doi: 10.1056/NEJM198704093161501.
6
Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.淋巴因子激活的杀伤现象剖析。外周血自然杀伤细胞和T淋巴细胞对细胞溶解的相对贡献。
J Exp Med. 1986 Sep 1;164(3):814-25. doi: 10.1084/jem.164.3.814.
7
Lymphokine-activated killer cells. Analysis of progenitors and effectors.淋巴因子激活的杀伤细胞。祖细胞和效应细胞的分析。
J Exp Med. 1986 Oct 1;164(4):1193-205. doi: 10.1084/jem.164.4.1193.
8
Lectin-dependent and anti-CD3 induced cytotoxicity are preferentially mediated by peripheral blood cytotoxic T lymphocytes expressing Leu-7 antigen.凝集素依赖性和抗CD3诱导的细胞毒性优先由表达Leu-7抗原的外周血细胞毒性T淋巴细胞介导。
J Immunol. 1986 Mar 1;136(5):1579-85.
9
Interleukin-2-dependent long-term cultures of low-density lymphocytes allow the proliferation of lymphokine-activated killer cells with natural killer, Ti gamma/delta or TNK phenotype.白细胞介素-2依赖的低密度淋巴细胞长期培养可使具有自然杀伤细胞、Tiγ/δ或TNK表型的淋巴因子激活的杀伤细胞增殖。
Cancer Immunol Immunother. 1990;31(1):11-8. doi: 10.1007/BF01742490.