Tomà P, Costa A, Magnano G M, Cariati M, Lituania M
Servizio di Radiologia, Instituto Giannina Gaslini, Genova, Italy.
Prenat Diagn. 1990 Jul;10(7):429-36. doi: 10.1002/pd.1970100704.
Magnetic resonance (MR) imaging was performed on two women at the 33rd and 34th pregnancy week, respectively, after ultrasonographic detection of a brain malformation. Fetal neuromuscular blockade was induced by pancuronium bromide injected into the umbilical vein under continuous ultrasound (US) guidance. MR images supported the echotomographic diagnosis of holoprosencephaly, improving the image quality and offering additional information in such cases of difficult differential fetal diagnosis. Holoprosencephaly was finally confirmed by neonatal US and autopsy (case 1), US, CT and MR (case 2).
在超声检测到脑畸形后，分别对两名处于妊娠第33周和第34周的女性进行了磁共振（MR）成像检查。在持续超声（US）引导下，通过向脐静脉注射泮库溴铵诱导胎儿神经肌肉阻滞。MR图像支持了超声断层扫描对前脑无裂畸形的诊断，提高了图像质量，并为这种胎儿鉴别诊断困难的病例提供了额外信息。前脑无裂畸形最终通过新生儿超声和尸检（病例1）、超声、CT和MR（病例2）得以确诊。
