Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
J Mass Spectrom. 2012 Feb;47(2):201-7. doi: 10.1002/jms.2955.
Methods and devices that use gas flows to collect ions and transfer them over long distances for mass spectrometric analysis have been developed. Gas flows derived from the ionization source itself or provided by means of additional pumping were used to generate a laminar flow inside cylindrical tube. Hydrodynamic simulations and experimental tests demonstrate that laminar flow can transfer ions over long distance. The typical angular discrimination effects encountered when sampling ions from ambient ionization sources are minimized, and the sampling of relatively large surface areas is demonstrated with desorption electrospray ionization (DESI). Ion transfer over 6 m has been achieved and its application to multiplexed chemical analysis is demonstrated on samples at locations remote from the mass spectrometer.
已经开发出了使用气流收集离子并将其远距离传输用于质谱分析的方法和设备。这些气流源自于离子源本身或者通过额外的抽气来提供，用于在圆柱管内产生层流。流体动力学模拟和实验测试表明，层流可以远距离传输离子。当从环境离子源中采样离子时，典型的角度辨别效应最小化，并且利用解吸电喷雾电离（DESI）证明了较大表面积的采样。已经实现了离子传输超过 6 米，并将其应用于远离质谱仪的位置的样品的多路化学分析中。
