CBMN, UMR 5248, CNRS, 2 rue Robert Escarpit, 33600 Pessac, France.
J Chem Phys. 2012 Feb 14;136(6):065102. doi: 10.1063/1.3682472.
A model that preserves the known thermodynamic properties of double stranded DNA is introduced to study the formation of more complex DNA constructions, such as small origamis or Holliday junctions. We show that the thermodynamic behaviour of these complex DNA constructions is not only given by their sequence but also by their topology.
引入了一种保留双链 DNA 已知热力学性质的模型,以研究更复杂的 DNA 结构的形成,例如小型折纸或 Holliday 连接。我们表明,这些复杂 DNA 结构的热力学行为不仅由其序列决定,还由其拓扑结构决定。